ZFIN ID: ZDB-LAB-111117-3
Burgess & Lin Lab
PI/Director: Burgess, Shawn
Lin, Shuo
Contact Person:
Line Designation: la

Show first 50 of 15,225 genomic features



Wilkes, M.C., Siva, K., Varetti, G., Mercado, J., Wentworth, E.P., Perez, C.A., Saxena, M., Kam, S., Kapur, S., Chen, J., Narla, A., Glader, B., Lin, S., Serrano, M., Flygare, J., Sakamoto, K.M. (2020) Metformin-induced suppression of Nemo-like kinase improves erythropoiesis in preclinical models of Diamond-Blackfan anemia through induction of miR-26a. Experimental hematology. 91:65-77
Ichino, N., Serres, M.R., Urban, R.M., Urban, M.D., Treichel, A.J., Schaefbauer, K.J., Greif, L.E., Varshney, G.K., Skuster, K.J., McNulty, M.S., Daby, C.L., Wang, Y., Liao, H.K., El-Rass, S., Ding, Y., Liu, W., Anderson, J.L., Wishman, M.D., Sabharwal, A., Schimmenti, L.A., Sivasubbu, S., Balciunas, D., Hammerschmidt, M., Farber, S.A., Wen, X.Y., Xu, X., McGrail, M., Essner, J.J., Burgess, S.M., Clark, K.J., Ekker, S.C. (2020) Building the vertebrate codex using the gene breaking protein trap library. eLIFE. 9:
Banote, R.K., Chebli, J., Şatır, T.M., Varshney, G.K., Camacho, R., Ledin, J., Burgess, S.M., Abramsson, A., Zetterberg, H. (2020) Amyloid precursor protein-b facilitates cell adhesion during early development in zebrafish. Scientific Reports. 10:10127
Pei, W., Xu, L., Chen, Z., Slevin, C.C., Pettie, K.P., Wincovitch, S., NISC Comparative Sequencing Program, Burgess, S.M. (2020) A subset of SMN complex members have a specific role in tissue regeneration via ERBB pathway-mediated proliferation. NPJ Regenerative medicine. 5:6
Chen, C., Lu, M., Lin, S., Qin, W. (2020) The nuclear gene rpl18 regulates erythroid maturation via JAK2-STAT3 signaling in zebrafish model of Diamond-Blackfan anemia. Cell Death & Disease. 11:135
Bai, H., Liu, L., An, K., Lu, X., Harrison, M., Zhao, Y., Yan, R., Lu, Z., Li, S., Lin, S., Liang, F., Qin, W. (2020) CRISPR/Cas9-mediated precise genome modification by a long ssDNA template in zebrafish. BMC Genomics. 21:67
Rissone, A., Jimenez, E., Bishop, K., Carrington, B., Slevin, C., Wincovitch, S.M., Sood, R., Candotti, F., Burgess, S.M. (2019) A model for reticular dysgenesis shows impaired sensory organ development and hair cell regeneration linked to cellular stress. Disease models & mechanisms. 12(12):
McElderry, J., Carrington, B., Bishop, K., Kim, E., Pei, W., Chen, Z., Ramanagoudr-Bhojappa, R., Prakash, A., Burgess, S.M., Liu, P.P., Sood, R. (2019) Splicing factor DHX15 affects tp53 and mdm2 expression via alternate splicing and promoter usage. Human molecular genetics. 28(24):4173-4185
Chen, C., Huang, H., Yan, R., Lin, S., Qin, W. (2019) Loss of rps9 in Zebrafish Leads to p53-Dependent Anemia. G3 (Bethesda). 9(12):4149-4157
Youn, M., Huang, H., Chen, C., Kam, S., Wilkes, M.C., Chae, H.D., Sridhar, K.J., Greenberg, P.L., Glader, B., Narla, A., Lin, S., Sakamoto, K.M. (2019) MMP9 inhibition increases erythropoiesis in RPS14-deficient del(5q) MDS models through suppression of TGF-β pathways. Blood advances. 3:2751-2763
Acevedo-Canabal, A., Colón-Cruz, L., Rodriguez-Morales, R., Varshney, G.K., Burgess, S., González-Sepúlveda, L., Yudowski, G., Behra, M. (2019) Altered Swimming Behaviors in Zebrafish Larvae Lacking Cannabinoid Receptor 2. Cannabis and cannabinoid research. 4:88-101
Pei, W., Burgess, S.M. (2019) Microinjection in Zebrafish for Genome Editing and Functional Studies. Methods in molecular biology (Clifton, N.J.). 1874:459-474
Qin, W., Lu, X., Liu, Y., Bai, H., Li, S., Lin, S. (2018) Precise A•T to G•C base editing in the zebrafish genome. BMC Biology. 16:139
Rissone, A., Burgess, S.M. (2018) Rare Genetic Blood Disease Modeling in Zebrafish. Frontiers in genetics. 9:348
Unal Eroglu, A., Mulligan, T.S., Zhang, L., White, D.T., Sengupta, S., Nie, C., Lu, N.Y., Qian, J., Xu, L., Pei, W., Burgess, S.M., Saxena, M.T., Mumm, J.S. (2018) Multiplexed CRISPR/Cas9 Targeting of Genes Implicated in Retinal Regeneration and Degeneration. Frontiers in cell and developmental biology. 6:88
Tseng, W.C., Loeb, H.E., Pei, W., Tsai-Morris, C.H., Xu, L., Cluzeau, C.V., Wassif, C.A., Feldman, B., Burgess, S.M., Pavan, W.J., Porter, F.D. (2018) Modeling Niemann-Pick disease type C1 in zebrafish: a robust platform for in vivo screening of candidate therapeutic compounds.. Disease models & mechanisms. 11(9)
Qin, W., Lu, X., Lin, S. (2018) Programmable base editing in zebrafish using a modified CRISPR-Cas9 system. Methods (San Diego, Calif.). 150:19-23
Pei, W., Xu, L., Huang, S.C., Pettie, K., Idol, J., Rissone, A., Jimenez, E., Sinclair, J.W., Slevin, C., Varshney, G.K., Jones, M., Carrington, B., Bishop, K., Huang, H., Sood, R., Lin, S., Burgess, S.M. (2018) Guided genetic screen to identify genes essential in the regeneration of hair cells and other tissues. NPJ Regenerative medicine. 3:11
Danilova, N., Wilkes, M., Bibikova, E., Youn, M.Y., Sakamoto, K.M., Lin, S. (2018) Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia. Scientific Reports. 8:5165
Lu, X., Liu, Y., Yan, G., Li, S., Qin, W., Lin, S. (2018) Optimized Target-AID system efficiently induces single base changes in zebrafish. Journal of genetics and genomics = Yi chuan xue bao. 45(4):215-217
Giannelou, A., Wang, H., Zhou, Q., Park, Y.H., Abu-Asab, M.S., Ylaya, K., Stone, D.L., Sediva, A., Sleiman, R., Sramkova, L., Bhatla, D., Serti, E., Tsai, W.L., Yang, D., Bishop, K., Carrington, B., Pei, W., Deuitch, N., Brooks, S., Edwan, J.H., Joshi, S., Prader, S., Kaiser, D., Owen, W.C., Sonbul, A.A., Zhang, Y., Niemela, J.E., Burgess, S.M., Boehm, M., Rehermann, B., Chae, J., Quezado, M.M., Ombrello, A.K., Buckley, R.H., Grom, A.A., Remmers, E.F., Pachlopnik, J.M., Su, H.C., Gutierrez-Cruz, G., Hewitt, S.M., Sood, R., Risma, K., Calvo, K.R., Rosenzweig, S.D., Gadina, M., Hafner, M., Sun, H.W., Kastner, D.L., Aksentijevich, I. (2018) Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors. Annals of the rheumatic diseases. 77(4):612-619
Crawford, N.G., Kelly, D.E., Hansen, M.E.B., Beltrame, M.H., Fan, S., Bowman, S.L., Jewett, E., Ranciaro, A., Thompson, S., Lo, Y., Pfeifer, S.P., Jensen, J.D., Campbell, M.C., Beggs, W., Hormozdiari, F., Mpoloka, S.W., Mokone, G.G., Nyambo, T., Wolde Meskel, D., Belay, G., Haut, J., Rothschild, H., Zon, L., Zhou, Y., Kovacs, M.A., Xu, M., Zhang, T., Bishop, K., Sinclair, J., Rivas, C., Elliot, E., Choi, J., Li, S.A., Hicks, B., Burgess, S., Abnet, C., Watkins-Chow, D.E., Oceana, E., Song, Y.S., Eskin, E., Brown, K.M., Marks, M.S., Loftus, S.K., Pavan, W.J., Yeager, M., Chanock, S., Tishkoff, S. (2017) Loci associated with skin pigmentation identified in African populations. Science (New York, N.Y.). 358(6365)
Feng, Z., Nam, S., Hamouri, F., Aujard, I., Ducos, B., Vriz, S., Volovitch, M., Jullien, L., Lin, S., Weiss, S., Bensimon, D. (2017) Optical Control of Tumor Induction in the Zebrafish. Scientific Reports. 7:9195
Zhang, Y., Qin, W., Lu, X., Xu, J., Huang, H., Bai, H., Li, S., Lin, S. (2017) Programmable base editing of zebrafish genome using a modified CRISPR-Cas9 system. Nature communications. 8:118
Li, H., Pei, W., Vergarajauregui, S., Zerfas, P.M., Raben, N., Burgess, S.M., Puertollano, R. (2017) Novel Degenerative and Developmental Defects in a Zebrafish Model of Mucolipidosis Type IV. Human molecular genetics. 26(14):2701-2718
Zhang, Y., Huang, H., Zhao, G., Yokoyama, T., Vega, H., Huang, Y., Sood, R., Bishop, K., Maduro, V., Accardi, J., Toro, C., Boerkoel, C.F., Lyons, K., Gahl, W.A., Duan, X., Malicdan, M.C., Lin, S. (2017) ATP6V1H Deficiency Impairs Bone Development through Activation of MMP9 and MMP13. PLoS Genetics. 13:e1006481
Varshney, G.K., Carrington, B., Pei, W., Bishop, K., Chen, Z., Fan, C., Xu, L., Jones, M., LaFave, M.C., Ledin, J., Sood, R., Burgess, S.M. (2016) A high-throughput functional genomics workflow based on CRISPR/Cas9-mediated targeted mutagenesis in zebrafish. Nature Protocols. 11:2357-2375
Pei, W., Huang, S.C., Xu, L., Pettie, K., Ceci, M.L., Sánchez, M., Allende, M.L., Burgess, S.M. (2016) Loss of Mgat5a-mediated N-glycosylation stimulates regeneration in zebrafish.. Cell regeneration (London, England). 5:3
Pei, S., Liu, L., Zhong, Z., Wang, H., Lin, S., Shang, J. (2016) Risk of prenatal depression and stress treatment: alteration on serotonin system of offspring through exposure to Fluoxetine. Scientific Reports. 6:33822
Feng, Y., Chen, C., Han, Y., Chen, Z., Lu, X., Liang, F., Li, S., Qin, W., Lin, S. (2016) Expanding CRISPR/Cas9 Genome Editing Capacity in Zebrafish Using SaCas9. G3 (Bethesda). 6(8):2517-21
Zhao, H., Osborne, O.J., Lin, S., Ji, Z., Damoiseux, R., Wang, Y., Nel, A.E., Lin, S. (2016) Lanthanide Hydroxide Nanoparticles Induce Angiogenesis via ROS-Sensitive Signaling. Small (Weinheim an der Bergstrasse, Germany). 12(32):4404-11
Pei, W., Xu, L., Varshney, G.K., Carrington, B., Bishop, K., Jones, M., Huang, S.C., Idol, J., Pretorius, P.R., Beirl, A., Schimmenti, L.A., Kindt, K.S., Sood, R., Burgess, S.M. (2016) Additive reductions in zebrafish PRPS1 activity result in a spectrum of deficiencies modeling several human PRPS1-associated diseases. Scientific Reports. 6:29946
Ear, J., Hsueh, J., Nguyen, M., Zhang, Q., Sung, V., Chopra, R., Sakamoto, K.M., Lin, S. (2016) A Zebrafish Model of 5q-Syndrome Using CRISPR/Cas9 Targeting RPS14 Reveals a p53-Independent and p53-Dependent Mechanism of Erythroid Failure. Journal of genetics and genomics = Yi chuan xue bao. 43(5):307-18
Vrljicak, P., Tao, S., Varshney, G.K., Quach, H.N., Joshi, A., LaFave, M.C., Burgess, S.M., Sampath, K. (2016) Genome-Wide Analysis of Transposon and Retroviral Insertions Reveals Preferential Integrations in Regions of DNA Flexibility. G3 (Bethesda). 6(4):805-17
Wu, W., Hai, Y., Chen, L., Liu, R.J., Han, Y.X., Li, W.H., Li, S., Lin, S., Wu, X.R. (2016) Deguelin-induced blockade of PI3K/protein kinase B/MAP kinase signaling in zebrafish and breast cancer cell lines is mediated by down-regulation of fibroblast growth factor receptor 4 activity. Pharmacology research & perspectives. 4:e00212
Varshney, G.K., Zhang, S., Pei, W., Adomako-Ankomah, A., Fohtung, J., Schaffer, K., Carrington, B., Maskeri, A., Slevin, C., Wolfsberg, T., Ledin, J., Sood, R., Burgess, S.M. (2016) CRISPRz: a database of zebrafish validated sgRNAs. Nucleic acids research. 44(D1):D822-6
Huang, P., Xiao, A., Tong, X., Lin, S., Zhang, B. (2016) Targeted Mutagenesis in Zebrafish by TALENs. Methods in molecular biology (Clifton, N.J.). 1338:191-206
Planchart, A., Mattingly, C.J., Allen, D., Ceger, P., Casey, W., Hinton, D., Kanungo, J., Kullman, S.W., Tal, T., Bondesson, M., Burgess, S.M., Sullivan, C., Kim, C., Behl, M., Padilla, S., Reif, D.M., Tanguay, R.L., Hamm, J. (2016) Advancing toxicology research using in vivo high throughput toxicology with small fish models. Altex. 33(4):435-452
Zhang, Y., Huang, H., Zhang, B., Lin, S. (2016) TALEN- and CRISPR-enhanced DNA homologous recombination for gene editing in zebrafish. Methods in cell biology. 135:107-20
Zhao, H., Huang, H., Lin, S. (2016) Chemical approaches to angiogenesis in development and regeneration. Methods in cell biology. 134:369-76
Carrington, B., Varshney, G.K., Burgess, S.M., Sood, R. (2015) CRISPR-STAT: an easy and reliable PCR-based method to evaluate target-specific sgRNA activity. Nucleic acids research. 43(22):e157
Veldman, M.B., Rios-Galdamez, Y., Lu, X.H., Gu, X., Qin, W., Li, S., Yang, X.W., Lin, S. (2015) The N17 domain mitigates nuclear toxicity in a novel zebrafish Huntington's disease model. Molecular neurodegeneration. 10:67
Varshney, G.K., Zhang, S., Burgess, S.M., ZFIN Staff (2015) Automated Data Load From CRISPRz. ZFIN Direct Data Submission.
Marquart, G.D., Tabor, K.M., Brown, M., Strykowski, J.L., Varshney, G.K., LaFave, M.C., Mueller, T., Burgess, S.M., Higashijima, S., Burgess, H.A. (2015) A 3D Searchable Database of Transgenic Zebrafish Gal4 and Cre Lines for Functional Neuroanatomy Studies. Frontiers in neural circuits. 9:78
Osborne, O.J., Lin, S., Chang, C.H., Ji, Z., Yu, X., Wang, X., Lin, S., Xia, T., Nel, A.E. (2015) Organ-Specific and Size-Dependent Ag Nanoparticle Toxicity in Gills and Intestines of Adult Zebrafish. ACS nano. 9(10):9573-84
Liang, F., Han, Y., Gao, H., Xin, S., Chen, S., Wang, N., Qin, W., Zhong, H., Lin, S., Yao, X., Li, S. (2015) Kaempferol Identified by Zebrafish Assay and Fine Fractionations Strategy from Dysosma versipellis Inhibits Angiogenesis through VEGF and FGF Pathways. Scientific Reports. 5:14468
Marquart, G.D., Tabor, K.M., Brown, M., Strykowski, J.L., Varshney, G.K., LaFave, M.C., Mueller, T., Burgess, S.H., Higashijima, S., and Burgess, H.A. (2015) Enhancer Trap Transgenics. ZFIN Direct Data Submission.
Ear, J., Huang, H., Wilson, T., Tehrani, Z., Lindgren, A., Sung, V., Laadem, A., Daniel, T.O., Chopra, R., Lin, S. (2015) RAP-011 improves erythropoiesis in zebrafish model of Diamond-Blackfan anemia through antagonizing lefty1. Blood. 126(7):880-90
Seiler, C., Gebhart, N., Zhang, Y., Shinton, S.A., Li, Y.S., Ross, N.L., Liu, X., Li, Q., Bilbee, A.N., Varshney, G.K., LaFave, M.C., Burgess, S.M., Balciuniene, J., Balciunas, D., Hardy, R.R., Kappes, D.J., Wiest, D.L., Rhodes, J. (2015) Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish. PLoS One. 10:e0131908
Marchegiani, S., Davis, T., Tessadori, F., van Haaften, G., Brancati, F., Hoischen, A., Huang, H., Valkanas, E., Pusey, B., Schanze, D., Venselaar, H., Vulto-van Silfhout, A.T., Wolfe, L.A., Tifft, C.J., Zerfas, P.M., Zambruno, G., Kariminejad, A., Sabbagh-Kermani, F., Lee, J., Tsokos, M.G., Lee, C.R., Ferraz, V., da Silva, E.M., Stevens, C.A., Roche, N., Bartsch, O., Farndon, P., Bermejo-Sanchez, E., Brooks, B.P., Maduro, V., Dallapiccola, B., Ramos, F.J., Chung, H.B., Le Caignec, C., Martins, F., Jacyk, W.K., Mazzanti, L., Brunner, H.G., Bakkers, J., Lin, S., Malicdan, M.C., Boerkoel, C.F., Gahl, W.A., de Vries, B.B., van Haelst, M.M., Zenker, M., Markello, T.C. (2015) Recurrent Mutations in the Basic Domain of TWIST2 Cause Ablepharon Macrostomia and Barber-Say Syndromes. American journal of human genetics. 97(1):99-110
Varshney, G.K., Pei, W., LaFave, M.C., Idol, J., Xu, L., Gallardo, V., Carrington, B., Bishop, K., Jones, M., Li, M., Harper, U., Huang, S.C., Prakash, A., Chen, W., Sood, R., Ledin, J., Burgess, S.M. (2015) High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9. Genome research. 25(7):1030-42
Gallardo, V.E., Varshney, G.K., Lee, M., Bupp, S., Xu, L., Shinn, P., Crawford, N.P., Inglese, J., Burgess, S.M. (2015) Phenotype-driven chemical screening in zebrafish for collective cell migration inhibitors identifies multiple potential pathways for targeting metastasis. Disease models & mechanisms. 8(6):565-76
Yin, L., Maddison, L.A., Li, M., Kara, N., LaFave, M.C., Varshney, G.K., Burgess, S.M., Patton, J.G., Chen, W. (2015) Multiplex Conditional Mutagenesis Using Transgenic Expression of Cas9 and sgRNAs. Genetics. 200(2):431-41
Quach, H.N., Tao, S., Vrljicak, P., Joshi, A., Ruan, H., Sukumaran, R., Varshney, G.K., LaFave, M.C., Screen Team, T.D., Burgess, S.M., Winkler, C., Emelyanov, A., Parinov, S., Sampath, K. (2015) A Multifunctional Mutagenesis System for Analysis of Gene Function in Zebrafish. G3 (Bethesda). 5(6):1283-99
Lindgren, A.G., Veldman, M.B., Lin, S. (2015) ETV2 expression increases the efficiency of primitive endothelial cell derivation from human embryonic stem cells. Cell regeneration (London, England). 4:1
Varshney, G.K., Sood, R., Burgess, S.M. (2015) Understanding and Editing the Zebrafish Genome. Advances in genetics. 92:1-52
Bibikova, E., Youn, M.Y., Danilova, N., Ono-Uruga, Y., Konto-Ghiorghi, Y., Ochoa, R., Narla, A., Glader, B., Lin, S., Sakamoto, K.M. (2014) TNF-mediated inflammation represses GATA1 and activates p38 MAP kinase in RPS19-deficient hematopoietic progenitors. Blood. 124(25):3791-8
Veldman, M.B., Lin, S. (2014) Stem Cells on Fire: Inflammatory Signaling in HSC Emergence. Developmental Cell. 31:517-518
Yuan, Y., Zhang, Y., Yao, S., Shi, H., Huang, X., Li, Y., Wei, Y., Lin, S. (2014) The translation initiation factor Eif3i upregulates vascular endothelial growth factor A, accelerates cell proliferation, and promotes angiogenesis in embryonic development and tumorigenesis. The Journal of biological chemistry. 289(41):28310-23
Hüsken, U., Stickney, H.L., Gestri, G., Bianco, I.H., Faro, A., Young, R.M., Roussigne, M., Hawkins, T.A., Beretta, C.A., Brinkmann, I., Paolini, A., Jacinto, R., Albadri, S., Dreosti, E., Tsalavouta, M., Schwarz, Q., Cavodeassi, F., Barth, A.K., Wen, L., Zhang, B., Blader, P., Yaksi, E., Poggi, L., Zigman, M., Lin, S., Wilson, S.W., Carl, M. (2014) Tcf7l2 Is Required for Left-Right Asymmetric Differentiation of Habenular Neurons. Current biology : CB. 24(19):2217-27
LaFave, M.C., Varshney, G.K., Vemulapalli, M., Mullikin, J.C., Burgess, S.M. (2014) A Defined Zebrafish Line for High-Throughput Genetics and Genomics: NHGRI-1. Genetics. 198(1):167-70
Zhang, Y., Ear, J., Yang, Z., Morimoto, K., Zhang, B., Lin, S. (2014) Defects of protein production in erythroid cells revealed in a zebrafish Diamond-Blackfan anemia model for mutation in RPS19. Cell Death & Disease. 5:e1352
Danilova, N., Bibikova, E., Covey, T.M., Nathanson, D., Dimitrova, E., Konto, Y., Lindgren, A., Glader, B., Radu, C.G., Sakamoto, K.M., Lin, S. (2014) The role of DNA damage response in zebrafish and cellular models of Diamond Blackfan Anemia. Disease models & mechanisms. 7(7):895-905
Qin, W., Chen, Z., Zhang, Y., Yan, R., Yan, G., Li, S., Zhong, H., Lin, S. (2014) Nom1 Mediates Pancreas Development by Regulating Ribosome Biogenesis in Zebrafish. PLoS One. 9:e100796
Carayannopoulos, M.O., Xiong, F., Jensen, P., Rios-Galdamez, Y., Huang, H., Lin, S., Devaskar, S.U. (2014) GLUT3 gene expression is critical for embryonic growth, brain development and survival. Molecular genetics and metabolism. 111:477-83
Zhou, Q., Yang, D., Ombrello, A.K., Zavialov, A.V., Toro, C., Zavialov, A.V., Stone, D.L., Chae, J.J., Rosenzweig, S.D., Bishop, K., Barron, K.S., Kuehn, H.S., Hoffmann, P., Negro, A., Tsai, W.L., Cowen, E.W., Pei, W., Milner, J.D., Silvin, C., Heller, T., Chin, D.T., Patronas, N.J., Barber, J.S., Lee, C.C., Wood, G.M., Ling, A., Kelly, S.J., Kleiner, D.E., Mullikin, J.C., Ganson, N.J., Kong, H.H., Hambleton, S., Candotti, F., Quezado, M.M., Calvo, K.R., Alao, H., Barham, B.K., Jones, A., Meschia, J.F., Worrall, B.B., Kasner, S.E., Rich, S.S., Goldbach-Mansky, R., Abinun, M., Chalom, E., Gotte, A.C., Punaro, M., Pascual, V., Verbsky, J.W., Torgerson, T.R., Singer, N.G., Gershon, T.R., Ozen, S., Karadag, O., Fleisher, T.A., Remmers, E.F., Burgess, S.M., Moir, S.L., Gadina, M., Sood, R., Hershfield, M.S., Boehm, M., Kastner, D.L., Aksentijevich, I. (2014) Early-onset stroke and vasculopathy associated with mutations in ADA2. The New England Journal of Medicine. 370(10):911-920
Varshney, G.K., and Burgess, S.M. (2014) Mutagenesis and phenotyping resources in zebrafish for studying development and human disease. Briefings in Functional Genomics. 13(2):82-94
Xu, H., Ye, D., Behra, M., Burgess, S., Chen, S., and Lin, F. (2014) Gbeta1 controls collective cell migration by regulating the protrusive activity of leader cells in the posterior lateral line primordium. Developmental Biology. 385(2):316-27
Tong, X., Zu, Y., Li, Z., Li, W., Ying, L., Yang, J., Wang, X., He, S., Liu, D., Zhu, Z., Chen, J., Lin, S., and Zhang, B. (2014) Kctd10 regulates heart morphogenesis by repressing the transcriptional activity of Tbx5a in zebrafish. Nature communications. 5:3153
Rothschild, S.C., Lahvic, J., Francescatto, L., McLeod, J.J., Burgess, S.M., and Tombes, R.M. (2013) CaMK-II activation is essential for zebrafish inner ear development and acts through Delta-Notch signaling. Developmental Biology. 381(1):179-88
Xia, Z., Tong, X., Liang, F., Zhang, Y., Kuok, C., Zhang, Y., Liu, X., Zhu, Z., Lin, S., and Zhang, B. (2013) Eif3ba regulates cranial neural crest development by modulating p53 in zebrafish. Developmental Biology. 381(1):83-96
Ren, G., Li, S., Zhong, H., and Lin, S. (2013) Zebrafish tyrosine hydroxylase 2 Gene Encodes Tryptophan Hydroxylase. The Journal of biological chemistry. 288(31):22451-9
Xiao, A., Wang, Z., Hu, Y., Wu, Y., Luo, Z., Yang, Z., Zu, Y., Li, W., Huang, P., Tong, X., Zhu, Z., Lin, S., and Zhang, B. (2013) Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish. Nucleic acids research. 41(14):e141
Wang, L., Liu, T., Xu, L., Gao, Y., Wei, Y., Duan, C., Chen, G.Q., Lin, S., Patient, R., Zhang, B., Hong, D., and Liu, F. (2013) Fev regulates hematopoietic stem cell development via ERK signaling. Blood. 122(3):367-75
Zhao, Y., and Lin, S. (2013) Essential Role of Sh3gl3 for Vascular Lumen Maintenance in Zebrafish. Arterioscler. Thromb. Vasc. Biol.. 33(6):1280-6
Lin, S., Zhao, Y., Ji, Z., Ear, J., Chang, C.H., Zhang, H., Low-Kam, C., Yamada, K., Meng, H., Wang, X., Liu, R., Pokhrel, S., Mädler, L., Damoiseaux, R., Xia, T., Godwin, H.A., Lin, S., and Nel, A.E. (2013) Zebrafish High-Throughput Screening to Study the Impact of Dissolvable Metal Oxide Nanoparticles on the Hatching Enzyme, ZHE1. Small (Weinheim an der Bergstrasse, Germany). 9(9-10):1776-85
Lin, S., Zhao, Y., Nel, A.E., and Lin, S. (2013) Zebrafish: An In Vivo Model for Nano EHS Studies. Small (Weinheim an der Bergstrasse, Germany). 9(9-10):1608-18
Lu, J., Xin, S., Meng, H., Veldman, M., Schoenfeld, D., Che, C., Yan, R., Zhong, H., Li, S., and Lin, S. (2013) A Novel Anti-Tumor Inhibitor Identified by Virtual Screen with PLK1 Structure and Zebrafish Assay. PLoS One. 8(4):e53317
Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
Zu, Y., Tong, X., Wang, Z., Liu, D., Pan, R., Li, Z., Hu, Y., Luo, Z., Huang, P., Wu, Q., Zhu, Z., Zhang, B., and Lin, S. (2013) TALEN-mediated precise genome modification by homologous recombination in zebrafish. Nature Methods. 10(4):329-31
Tong, X., Xia, Z., Zu, Y., Telfer, H., Hu, J., Yu, J., Liu, H., Zhang, Q., Sodmergen, D., Lin, S., and Zhang, B. (2013) Ngs (notochord granular surface) encodes a novel type of intermediate filament family protein essential for notochord maintenance in zebrafish. The Journal of biological chemistry. 288(4):2711-2720
Huang, P., Xu, L., Liang, W., Tam, C.I., Zhang, Y., Qi, F., Zhu, Z., Lin, S., and Zhang, B. (2013) Genomic deletion induced by Tol2 transposon excision in zebrafish. Nucleic acids research. 41(2):e36
Varshney, G.K., Zhang, S., Gildea, D.E., Wolfsberg, T.G., and Burgess, S.M. (2013) The Zebrafish Insertion Collection (ZInC): a web based, searchable collection of zebrafish mutations generated by DNA insertion. Nucleic acids research. 41(D1):D861-864
Veldman, M.B., Zhao, C., Gomez, G.A., Lindgren, A.G., Huang, H., Yang, H., Yao, S., Martin, B.L., Kimelman, D., and Lin, S. (2013) Transdifferentiation of fast skeletal muscle into functional endothelium in vivo by transcription factor etv2. PLoS Biology. 11(6):e1001590
Yuan, Y., Zhao, Y., Xin, S., Wu, N., Wen, J., Li, S., Chen, L., Wei, Y., Yang, H., and Lin, S. (2013) A Novel PEGylated Liposome-Encapsulated SANT75 Suppresses Tumor Growth through Inhibiting Hedgehog Signaling Pathway. PLoS One. 8(4):e60266
Burgess, S., and Lin, S. (2012) Viral Insertion Mutants Overwrite Data. ZFIN Direct Data Submission.
Huang, H., Lindgren, A., Wu, X., Liu, N.A., and Lin, S. (2012) High-throughput screening for bioactive molecules using primary cell culture of transgenic zebrafish embryos. Cell Reports. 2(3):695-704
Huang, P., Zhu, Z., Lin, S., and Zhang, B. (2012) Reverse genetic approaches in zebrafish. Journal of genetics and genomics = Yi chuan xue bao. 39(9):421-433
Burgess, S.M. (2012) The changing conditions of zebrafish mutants. Proceedings of the National Academy of Sciences of the United States of America. 109(38):15082-15083
Xu, L., Feng, Z., Sinha, D., Ducos, B., Ebenstein, Y., Tadmor, A.D., Gauron, C., Le Saux, T., Lin, S., Weiss, S., Vriz, S., Jullien, L., and Bensimon, D. (2012) Spatiotemporal manipulation of retinoic acid activity in zebrafish hindbrain development via photo-isomerization. Development (Cambridge, England). 139(18):3355-3362
Liang, J., Wang, D., Renaud, G., Wolfsberg, T.G., Wilson, A.F., and Burgess, S.M. (2012) The stat3/socs3a Pathway Is a Key Regulator of Hair Cell Regeneration in Zebrafish stat3/socs3a Pathway: Regulator of Hair Cell Regeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(31):10662-10673
Chen, L., Ren, X., Liang, F., Li, S., Zhong, H., and Lin, S. (2012) Characterization of two novel small molecules targeting melanocyte development in zebrafish embryogenesis. Pigment cell & melanoma research. 25(4):446-453
Yin, W., Liu, D., Liu, N., Xu, L., Li, S., Lin, S., Shu, X., Pei, D. (2012) SNX17 regulates Notch pathway and pancreas development through the retromer-dependent recycling of Jag1. Cell regeneration (London, England). 1:4
Xu, L., Yin, W., Xia, J., Peng, M., Li, S., Lin, S., Pei, A., and Shum, X. (2012) An anti-apoptotic role of SNX7 is required for liver development in zebrafish. Hepatology (Baltimore, Md.). 55(6):1985-1993
Lee, M.S., Bonner, J.R., Bernard, D.J., Sanchez, E.L., Sause, E.T., Prentice, R.R., Burgess, S.M., and Brody, L.C. (2012) Disruption of the folate pathway in zebrafish causes developmental defects. BMC Developmental Biology. 12(1):12
Chen, Y., Wu, B., Xu, L., Li, H., Xia, J., Yin, W., Li, Z., Li, S., Lin, S., Shu, X., and Pei, D. (2012) A SNX10/V-ATPase pathway regulates ciliogenesis in vitro and in vivo. Cell Research. 22(2):333-345
Behra, M., Gallardo, V.E., Bradsher, J., Torrado, A., Elkahloun, A., Idol, J., Sheehy, J., Zonies, S., Xu, L., Shaw, K.M., Satou, C., Higashijima, S.I., Weinstein, B.M., and Burgess, S.M. (2012) Transcriptional signature of accessory cells in the lateral line, using the Tnk1bp1:EGFP transgenic zebrafish line. BMC Developmental Biology. 12(1):6
Veldman, M.B., and Lin, S. (2012) Etsrp/Etv2 Is Directly Regulated by Foxc1a/b in the Zebrafish Angioblast. Circulation research. 110(2):220-229
Milla, L.A., Cortes, C.R., Hodar, C.Q., Onate, M.G., Cambiazo, V., Burgess, S.M., and Palma, V. (2012) Yeast-based assay identifies novel Shh/Gli target genes in vertebrate development. BMC Genomics. 13(1):2
Gomez, G., Lee, J.H., Veldman, M.B., Lu, J., Xiao, X., and Lin, S. (2012) Identification of Vascular and Hematopoietic Genes Downstream of etsrp by Deep Sequencing in Zebrafish. PLoS One. 7(3):e31658
Liu, H., Gomez, G., Lin, S., Lin, S., and Lin, C. (2012) Optogenetic control of transcription in zebrafish. PLoS One. 7(11):e50738
Yan, J., and Burgess, S.M. (2012) Using a yeast inverse one-hybrid system to identify functional binding sites of transcription factors. Methods in molecular biology (Clifton, N.J.). 786:275-290
Zhang, Y., Morimoto, K., Danilova, N., Zhang, B., and Lin, S. (2012) Zebrafish Models for Dyskeratosis Congenita Reveal Critical Roles of p53 Activation Contributing to Hematopoietic Defects through RNA Processing. PLoS One. 7(1):e30188
Tehrani, Z., and Lin, S. (2011) Endocrine pancreas development in zebrafish. Cell cycle (Georgetown, Tex.). 10(20):3466-3472
Burgess, S., and Lin, S. (2011) Viral Insertion Mutants. ZFIN Direct Data Submission.
Huang, P., Xiao, A., Zhou, M., Zhu, Z., Lin, S., and Zhang, B. (2011) Heritable gene targeting in zebrafish using customized TALENs. Nat. Biotechnol.. 29(8):699-700
Zhao, C., Yang, H., Shi, H., Wang, X., Chen, X., Yuan, Y., Lin, S., and Wei, Y. (2011) Distinct Contributions of Angiogenesis and Vascular Co-option during the Initiation of Primary Microtumors and Micrometastases. Carcinogenesis. 32(8):1143-50
Zhong, H., Wang, D., Wang, N., Rios, Y., Huang, H., Li, S., Wu, X., and Lin, S. (2011) Combinatory action of VEGFR2 and MAP kinase pathways maintains endothelial-cell integrity. Cell Research. 21(7):1080-7
Liu, N.A., Jiang, H., Ben-Shlomo, A., Wawrowsky, K., Fan, X.M., Lin, S., and Melmed, S. (2011) Targeting zebrafish and murine pituitary corticotroph tumors with a cyclin-dependent kinase (CDK) inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 108(20):8414-8419
George, S., Xia, T., Rallo, R., Zhao, Y., Ji, Z., Lin, S., Wang, X., Zhang, H., France, B., Schoenfeld, D., Damoiseaux, R., Liu, R., Lin, S., Bradley, K.A., Cohen, Y., and Nel, A.E. (2011) Use of a High-Throughput Screening Approach Coupled with In Vivo Zebrafish Embryo Screening To Develop Hazard Ranking for Engineered Nanomaterials. ACS nano. 5(3):1805-17
Xia, T., Zhao, Y., Sager, T., George, S., Pokhrel, S., Li, N., Schoenfeld, D., Meng, H., Lin, S., Wang, X., Wang, M., Ji, Z., Zink, J.I., Madler, L., Castranova, V., Lin, S., and Nel, A.E. (2011) Decreased Dissolution of ZnO by Iron Doping Yields Nanoparticles with Reduced Toxicity in the Rodent Lung and Zebrafish Embryos. ACS nano. 5(2):1223-1235
Huang, W., Deng, Y., Dong, W., Yuan, W., Wan, Y., Mo, X., Li, Y., Wang, Z., Wang, Y., Ocorr, K., Zhang, B., Lin, S., and Wu, X. (2011) The effect of excess expression of GFP in a novel heart-specific green fluorescence zebrafish regulated by nppa enhancer at early embryonic development. Molecular biology reports. 38(2):793-799
Tehrani, Z., and Lin, S. (2011) Antagonistic interactions of hedgehog, Bmp and retinoic acid signals control zebrafish endocrine pancreas development. Development (Cambridge, England). 138(4):631-640
Ríos, Y., Melmed, S., Lin, S., and Liu, N.A. (2011) Zebrafish usp39 Mutation Leads to rb1 mRNA Splicing Defect and Pituitary Lineage Expansion. PLoS Genetics. 7(1):e1001271
Amsterdam, A., Varshney, G.K., and Burgess, S.M. (2011) Retroviral-mediated Insertional Mutagenesis in Zebrafish. Methods in cell biology. 104:59-82
Bai, X., Yang, Z., Jiang, H., Lin, S., and Zon, L.I. (2011) Genetic suppressor screens in haploids. Methods in cell biology. 104:129-136
Danilova, N., Sakamoto, K.M., and Lin, S. (2011) Ribosomal protein L11 mutation in zebrafish leads to haematopoietic and metabolic defects. British journal of haematology. 152(2):217-228
Gao, W., Xu, L., Guan, R., Liu, X., Han, Y., Wu, Q., Xiao, Y., Qi, F., Zhu, Z., Lin, S., and Zhang, B. (2011) Wdr18 Is Required for Kupffer's Vesicle Formation and Regulation of Body Asymmetry in Zebrafish. PLoS One. 6(8):e23386
Liang, J., Renaud, G., and Burgess, S.M. (2011) Sequencing-based Expression Profiling in Zebrafish. Methods in cell biology. 104:379-399
Ren, G., Xin, S., Li, S., Zhong, H., and Lin, S. (2011) Disruption of LRRK2 Does Not Cause Specific Loss of Dopaminergic Neurons in Zebrafish. PLoS One. 6(6):e20630
Zhao, C., Wang, X., Zhao, Y., Li, Z., Lin, S., Wei, Y., and Yang, H. (2011) A novel xenograft model in zebrafish for high-resolution investigating dynamics of neovascularization in tumors. PLoS One. 6(7):e21768
Zhong, H., and Lin, S. (2011) Chemical screening with zebrafish embryos. Methods in molecular biology (Clifton, N.J.). 716:193-205
Gallardo, V.E., Liang, J., Behra, M., Elkahloun, A., Villablanca, E.J., Russo, V., Allende, M.L., and Burgess, S.M. (2010) Molecular dissection of the migrating posterior lateral line primordium during early development in zebrafish. BMC Developmental Biology. 10:120
Mazilu, J.K., Powers, J.W., Lin, S., and McCabe, E.R. (2010) ff1b, the SF1 ortholog, is important for pancreatic islet cell development in zebrafish. Molecular genetics and metabolism. 101(4):391-394
Powers, J.W., Mazilu, J.K., Lin, S., and McCabe, E.R. (2010) The effects of hyperglycemia on adrenal cortex function and steroidogenesis in the zebrafish. Molecular genetics and metabolism. 101(4):421-422
Qi, F., Song, J., Yang, H., Gao, W., Liu, N.A., Zhang, B., and Lin, S. (2010) Mmp23b promotes liver development and hepatocyte proliferation through the tumor necrosis factor pathway in zebrafish. Hepatology (Baltimore, Md.). 52(6):2158-2166
Xue, Y., Kuok, C., Xiao, A., Zhu, Z., Lin, S., and Zhang, B. (2010) Identification and expression analysis of mical family genes in zebrafish. Journal of genetics and genomics = Yi chuan xue bao. 37(10):685-693
Zhong, H., Xin, S., Zhao, Y., Lu, J., Li, S., Gong, J., Yang, Z., and Lin, S. (2010) Genetic approach to evaluate specificity of small molecule drug candidates inhibiting PLK1 using zebrafish. Molecular Biosystems. 6(8):1463-1468
Bai, X., Kim, J., Yang, Z., Jurynec, M.J., Akie, T.E., Lee, J., LeBlanc, J., Sessa, A., Jiang, H., DiBiase, A., Zhou, Y., Grunwald, D.J., Lin, S., Cantor, A.B., Orkin, S.H., and Zon, L.I. (2010) TIF1gamma controls erythroid cell fate by regulating transcription elongation. Cell. 142(1):133-143
Ren, X., Gomez, G.A., Zhang, B., and Lin, S. (2010) Scl isoforms act downstream of etsrp to specify angioblasts and definitive hematopoietic stem cells. Blood. 115(26):5338-5346
Jagadeeswaran, P., Lin, S., Weinstein, B., Hutson, A., and Kim, S. (2010) Loss of GATA1 and gain of FLI1 expression during thrombocyte maturation. Blood cells, molecules & diseases. 44(3):175-180
Zhong, H., Zou, H., Semenov, M.V., Moshinsky, D., He, X., Huang, H., Li, S., Quan, J., Yang, Z., and Lin, S. (2009) Characterization and development of novel small-molecules inhibiting GSK3 and activating Wnt signaling. Molecular Biosystems. 5(11):1356-1360
Powers, J., Zhao, Y., Lin, S., and McCabe, E.R. (2009) The expression of nr0b1, the earliest gene in zebrafish tooth development, is a marker for human tooth and ameloblastoma formation. Development genes and evolution. 219(8):419-425
Yang, H., Xiang, J., Wang, N., Zhao, Y., Hyman, J., Jiang, J., Chen, J.K., Yang, Z., and Lin, S. (2009) Converse conformational control of smoothened activity by structurally related small molecules. The Journal of biological chemistry. 284(31):20876-20884
Liang, J., and Burgess, S.M. (2009) Gross and fine dissection of inner ear sensory epithelia in adult zebrafish (Danio rerio). Journal of visualized experiments : JoVE. (27)
Behra, M., Bradsher, J., Sougrat, R., Gallardo, V., Allende, M.L., and Burgess, S.M. (2009) Phoenix is required for mechanosensory hair cell regeneration in the zebrafish lateral line. PLoS Genetics. 5(4):e1000455
Bukrinsky, A., Griffin, K.J., Zhao, Y., Lin, S., and Banerjee, U. (2009) Essential role of spi-1-like (spi-1l) in zebrafish myeloid cell differentiation. Blood. 113(9):2038-2046
Gomez, G.A., Veldman, M.B., Zhao, Y., Burgess, S., and Lin, S. (2009) Discovery and characterization of novel vascular and hematopoietic genes downstream of etsrp in zebrafish. PLoS One. 4(3):e4994
Jao, L.E., and Burgess, S.M. (2009) Production of pseudotyped retrovirus and the generation of proviral transgenic zebrafish. Methods in molecular biology (Clifton, N.J.). 546:13-30
Xiang, J., Yang, H., Che, C., Zou, H., Yang, H., Wei, Y., Quan, J., Zhang, H., Yang, Z., and Lin, S. (2009) Identifying tumor cell growth inhibitors by combinatorial chemistry and zebrafish assays. PLoS One. 4(2):e4361
Yang, Z., Jiang, H., and Lin, S. (2009) Bacterial artificial chromosome transgenesis for zebrafish. Methods in molecular biology (Clifton, N.J.). 546:103-116
Yuan, Y., Lin, S., Zhu, Z., Zhang, W., and Lai, Z.C. (2009) The mob as tumor suppressor (mats1) gene is required for growth control in developing zebrafish embryos. The International journal of developmental biology. 53(4):525-533
Danilova, N., Sakamoto, K.M., and Lin, S. (2008) Ribosomal protein S19 deficiency in zebrafish leads to developmental abnormalities and defective erythropoiesis through activation of p53 protein family. Blood. 112(13):5228-5237
Jiang, Z., Song, J., Qi, F., Xiao, A., An, X., Liu, N.A., Zhu, Z., Zhang, B., and Lin, S. (2008) Exdpf is a key regulator of exocrine pancreas development controlled by retinoic acid and ptf1a in zebrafish. PLoS Biology. 6(11):e293
Jao, L.E., Maddison, L., Chen, W., and Burgess, S.M. (2008) Using retroviruses as a mutagenesis tool to explore the zebrafish genome. Briefings in functional genomics & proteomics. 7(6):427-443
Veldman, M.B., and Lin, S. (2008) Zebrafish as a developmental model organism for pediatric research. Pediatric Research. 64(5):470-476
Danilova, N., Sakamoto, K.M., and Lin, S. (2008) Role of p53 family in birth defects: Lessons from zebrafish. Birth defects research. Part C, Embryo today : reviews. 84(3):215-227
Liu, N.A., Ren, M., Song, J., Ríos, Y., Wawrowsky, K., Ben-Shlomo, A., Lin, S., and Melmed, S. (2008) In vivo time-lapse imaging delineates the zebrafish pituitary proopiomelanocortin lineage boundary regulated by FGF3 signal. Developmental Biology. 319(2):192-200
Mei, J., Zhang, Q.Y., Li, Z., Lin, S., and Gui, J.F. (2008) C1q-like inhibits p53-mediated apoptosis and controls normal hematopoiesis during zebrafish embryogenesis. Developmental Biology. 319(2):273-284
Wei, W., Wen, L., Huang, P., Zhang, Z., Chen, Y., Xiao, A., Huang, H., Zhu, Z., Zhang, B., and Lin, S. (2008) Gfi1.1 regulates hematopoietic lineage differentiation during zebrafish embryogenesis. Cell Research. 18(6):677-685
Sumanas, S., Gomez, G., Zhao, Y., Park, C., Choi, K., and Lin, S. (2008) Interplay between Etsrp/ER71, scl and alk8 signaling controls endothelial and myeloid cell formation. Blood. 111(9):4500-4510
Bergeron, S.A., Milla, L.A., Villegas, R., Shen, M.C., Burgess, S.M., Allende, M.L., Karlstrom, R.O., and Palma, V. (2008) Expression profiling identifies novel Hh/Gli-regulated genes in developing zebrafish embryos. Genomics. 91(2):165-177
Wen, L., Wei, W., Gu, W., Huang, P., Ren, X., Zhang, Z., Zhu, Z., Lin, S., and Zhang, B. (2008) Visualization of monoaminergic neurons and neurotoxicity of MPTP in live transgenic zebrafish. Developmental Biology. 314(1):84-92
Zeng, J., Yan, J., Wang, T., Mosbrook-Davis, D., Dolan, K.T., Christensen, R., Stormo, G.D., Haussler, D., Lathrop, R.H., Brachmann, R.K., and Burgess, S.M. (2008) Genome wide screens in yeast to identify potential binding sites and target genes of DNA-binding proteins. Nucleic acids research. 36(1):e8
Yang, Z., Jiang, H., Zhao, F., Shankar, D.B., Sakamoto, K.M., Zhang, M.Q., and Lin, S. (2007) A highly conserved regulatory element controls hematopoietic expression of GATA-2 in zebrafish. BMC Developmental Biology. 7(1):97
Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
Song, J., Kim, H.J., Gong, Z., Liu, N.A., and Lin, S. (2007) Vhnf1 acts downstream of Bmp, Fgf, and RA signals to regulate endocrine beta cell development in zebrafish. Developmental Biology. 303(2):561-575
Zhong, H., Li, Z., Lin, S., and Chang, Y. (2007) Initiation of V(D)J recombination in zebrafish (Danio rerio) ovaries. Molecular immunology. 44(7):1795-1803
Wang, H., Lee, E.M., Sperber, S.M., Lin, S., Ekker, M., and Long, Q. (2007) Isolation and expression of zebrafish zinc-finger transcription factor gene tsh1. Gene expression patterns : GEP. 7(3):318-322
Zhong, H., Wu, X., Huang, H., Fan, Q., Zhu, Z., and Lin, S. (2006) Vertebrate MAX-1 is required for vascular patterning in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 103(45):16800-16805
Burgess, S. (2006) New techniques for using zebrafish as a model for development. Methods (San Diego, Calif.). 39(3):181-182
Yang, Z., Jiang, H., Chachainasakul, T., Gong, S., Yang, X.W., Heintz, N., and Lin, S. (2006) Modified bacterial artificial chromosomes for zebrafish transgenesis. Methods (San Diego, Calif.). 39(3):183-188
Conway, G., Torrejon, M., Lin, S., and Reinsch, S. (2006) Fluorescent tagged analysis of neural gene function using mosaics in zebrafish and Xenopus laevis. Brain research. 1070(1):150-159
Kim, H.J., Sumanas, S., Palencia-Desai, S., Dong, Y., Chen, J.N., and Lin, S. (2006) Genetic analysis of early endocrine pancreas formation in zebrafish. Molecular endocrinology (Baltimore, Md.). 20(1):194-203
Kwan, T.T., Liang, R., Verfaillie, C.M., Ekker, S.C., Chan, L.C., Lin, S., and Leung, A.Y. (2006) Regulation of primitive hematopoiesis in zebrafish embryos by the death receptor gene. Experimental hematology. 34(1):27-34
Kim, H.J., Schleiffarth, J.R., Jessurun, J., Sumanas, S., Petryk, A., Lin, S., and Ekker, S.C. (2005) Wnt5 signaling in vertebrate pancreas development. BMC Biology. 3:23
Sumanas, S., Jorniak, T., and Lin, S. (2005) Identification of novel vascular endothelial-specific genes by the microarray analysis of the zebrafish cloche mutants. Blood. 106(2):534-541
Hardison, A.L., Lichten, L., Banerjee-Basu, S., Becker, T.S., and Burgess, S.M. (2005) The zebrafish gene claudinj is essential for normal ear function and important for the formation of the otoliths. Mechanisms of Development. 122(7-8):949-958
Qian, F., Zhen, F., Ong, C., Jin, S.W., Meng Soo, H., Stainier, D.Y., Lin, S., Peng, J., and Wen, Z. (2005) Microarray analysis of zebrafish cloche mutant using amplified cDNA and identification of potential downstream target genes. Developmental dynamics : an official publication of the American Association of Anatomists. 233(3):1163-1172
Sumanas, S., Zhang, B., Dai, R., and Lin, S. (2005) 15-Zinc finger protein Bloody Fingers is required for zebrafish morphogenetic movements during neurulation. Developmental Biology. 283(1):85-96
Huang, H., Zhang, B., Hartenstein, P.A., Chen, J.N., and Lin, S. (2005) NXT2 is required for embryonic heart development in zebrafish. BMC Developmental Biology. 5(1):7
Penberthy, W.T., Zhao, C., Zhang, Y., Jessen, J.R., Yang, Z., Bricaud, O., Collazo, A., Meng, A., and Lin, S. (2004) Pur alpha and Sp8 as opposing regulators of neural gata2 expression. Developmental Biology. 275(1):225-234
Ransom, D.G., Bahary, N., Niss, K., Traver, D., Burns, C., Trede, N.S., Paffett-Lugassy, N., Saganic, W.J., Lim, C.A., Hersey, C., Zhou, Y., Barut, B.A., Lin, S., Kingsley, P.D., Palis, J., Orkin, S.H., and Zon, L.I. (2004) The Zebrafish moonshine Gene Encodes Transcriptional Intermediary Factor 1gamma, an Essential Regulator of Hematopoiesis. PLoS Biology. 2(8):E237
Shafizadeh, E., Peterson, R.T., and Lin, S. (2004) Induction of reversible hemolytic anemia in living zebrafish using a novel small molecule. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 138(3):245-249
Ng, D., Thakker, N., Corcoran, C.M., Donnai, D., Perveen, R., Schneider, A., Hadley, D.W., Tifft, C., Zhang, L., Wilkie, A.O., Van Der Smagt, J.J,, Gorlin.,R.J., Burgess, S.M., Bardwell, V.J., Black, G.C., and Biesecker, L.G. (2004) Oculofaciocardiodental and Lenz microphthalmia syndromes result from distinct classes of mutations in BCOR. Nature Genetics. 36(4):411-416
Kurita, K., Burgess, S.M., and Sakai, N. (2004) Transgenic zebrafish produced by retroviral infection of in vitro-cultured sperm. Proceedings of the National Academy of Sciences of the United States of America. 101(5):1263-1267
Ju, B., Huang, H., Lee, K.Y., and Lin, S. (2004) Cloning zebrafish by nuclear transfer. The Zebrafish: Genetics, Genomics and Informatics, 2nd ed., Methods Cell Biol.. 77:403-411
Traver, D., Paw, B.H., Poss, K.D., Penberthy, W.T., Lin, S., and Zon, L.I. (2003) Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nature immunology. 4(12):1238-1246
Nissen, R.M., Yan, J., Amsterdam, A., Hopkins, N., and Burgess, S.M. (2003) Zebrafish foxi one modulates cellular responses to Fgf signaling required for the integrity of ear and jaw patterning. Development (Cambridge, England). 130(11):2543-2554
Cross, L.M., Cook, M.A., Lin, S., Chen, J.N., and Rubinstein, A.L. (2003) Rapid analysis of angiogenesis drugs in a live fluorescent zebrafish assay. Arterioscler. Thromb. Vasc. Biol.. 23(5):911-912
Liu, N.A., Huang, H., Yang, Z., Herzog, W., Hammerschmidt, M., Lin, S., and Melmed, S. (2003) Pituitary corticotroph ontogeny and regulation in transgenic zebrafish. Molecular endocrinology (Baltimore, Md.). 17(5):959-966
Brownlie, A., Hersey, C., Oates, A.C., Paw, B.H., Falick, A.M., Witkowska, H.E., Flint,J., Higgs, D., Jessen, J., Bahary, N., Zhu, H., Lin, S. and Zon, L. (2003) Characterization of embryonic globin genes of the zebrafish. Developmental Biology. 255(1):48-61
Langenau, D.M., Traver, D., Ferrando, A.A., Kutok, J.L., Aster, J.C., Kanki, J.P., Lin, S., Prochownik, E., Trede, N.S., Zon, L.I., and Look, A.T. (2003) Myc-induced T cell leukemia in transgenic zebrafish. Science (New York, N.Y.). 299(5608):887-890
Zeller, J., Schneider, V., Malayaman, S., Higashijima, S., Okamoto, H., Gui, J., Lin, S., and Granato, M. (2002) Migration of zebrafish spinal motor nerves into the periphery requires multiple myotome-derived cues. Developmental Biology. 252(2):241-256
Shafizadeh, E., Paw, B.H., Foott, H., Liao, E.C., Barut, B.A., Cope, J.J., Zon, L.I., and Lin, S. (2002) Characterization of zebrafish merlot/chablis as non-mammalian vertebrate models for severe congenital anemia due to protein 4.1 deficiency. Development (Cambridge, England). 129(18):4359-4370
Lee, K-Y., Huang, H., Ju, B., Yang, Z., and Lin, S. (2002) Cloned zebrafish by nuclear transfer from long-term-cultured cells. Nat. Biotechnol.. 20(8):795-799
Golling, G., Amsterdam, A., Sun, Z., Antonelli, M., Maldonado, E., Chen, W., Burgess, S., Haldi, M., Artzt, K., Farrington, S., Lin, S.Y., Nissen, R.M., and Hopkins, N. (2002) Insertional mutagenesis in zebrafish rapidly identifies genes essential for early vertebrate development. Nature Genetics. 31(2):135-140
Penberthy, W.T., Shafizadeh, E., and Lin, S. (2002) The zebrafish as a model for human disease. Frontiers in bioscience : a journal and virtual library. 7:9-1453
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Willett, C.E., Kawasaki, H., Amemiya, C.T., Lin, S., and Steiner, L.A. (2001) Ikaros expression as a marker for lymphoid progenitors during zebrafish development. Developmental dynamics : an official publication of the American Association of Anatomists. 222(4):694-698
Huang, H., Liu, N., and Lin, S. (2001) Pdx-1 knockdown reduces insulin promoter activity in zebrafish. Genesis (New York, N.Y. : 2000). 30(3):134-136
Wang, G., Huang, H., Dai, R., Lee, K.Y., Lin, S., and Mivechi, N.F. (2001) Suppression of heat shock transcription factor HSF1 in zebrafish causes heat-induced apoptosis. Genesis (New York, N.Y. : 2000). 30(3):195-197
Chen, W., Burgess, S., and Hopkins, N. (2001) Analysis of the zebrafish smoothened mutant reveals conserved and divergent functions of hedgehog activity. Development (Cambridge, England). 128(12):2385-2396
Huang, H., Vogel, S.S., Liu, N., Melton, D.A., and Lin, S. (2001) Analysis of pancreatic development in living transgenic zebrafish embryos. Molecular and Cellular Endocrinology. 177(1-2):117-124
Jessen, J.R., Jessen, T.N., Vogel, S.S., and Lin, S. (2001) Concurrent expression of recombination activating genes 1 and 2 in zebrafish olfactory sensory neurons. Genesis (New York, N.Y. : 2000). 29(4):156-162
Yang, Z., Liu, N., and Lin, S. (2001) A zebrafish forebrain-specific zinc finger gene can induce ectopic dlx2 and dlx6 expression. Developmental Biology. 231(1):138-148
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Long, Q., Quint, E., Lin, S., and Ekker, M. (2000) The zebrafish scyba gene encodes a novel CXC-type chemokine with distinctive expression patterns in the vestibulo-acoustic system during embryogenesis. Mechanisms of Development. 97(1-2):183-186
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