ZFIN Image: Du et al., 2024, Figure 6

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Figure Caption

Figure 6

Interaction between VD3 and gut microbiota under short-term fasting conditions. (A–F) Zebrafish were treated with an antibiotic cocktail (Abx) while fed a VD3 or non-VD3 diet for one month. The serum glucose levels (A) and serum GLP-1 levels (B) were assayed (n = 3 replicates, 4~5 fish/replicate). The expression levels of gcga (C), gcgb (D), pcsk1 (E) and pcsk2 (F) in the intestine were analyzed (n = 4/group). (G) GF zebrafish at 3 dpf were incubated with NaA, NaP, or NaB (30 mM) for two days. The gene expression of pcsk1 was determined (n = 5 replicates, 10 larvae/replicate). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001, # p < 0.05, ## p < 0.01, ### p < 0.001, ns: no statistical significance.

Acknowledgments

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