Image
Figure Caption

Figure 8—figure supplement 1. Paraxial mesoderm does not generate HSPCs.

(A) kdrl:Cre; A2BD and (B) tbx6:Gal4; Tg(UAS-Cre); A2BD adult kidney marrow was analyzed by flow cytometry. Top row illustrates that the hematopoietic lineages of kdrl:Cre; A2BD originate from switched DsRed+ ECs (A), whereas in the tbx6:Gal4; Tg(UAS-Cre); A2BD, BFP+ non-switched ECs are the source of the hematopoietic system. DsRED+ SDECs do not give rise to hematopoietic lineages (B).

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