Molecularly distinct Müller glia subpopulations differ in their spatial location. (A) Expression plots of key markers efnb2a, fgf24, and rdh10a. (B) RNAscope in situ hybridization of genes presented in (A), highlighting their location throughout the dorsal (top) to ventral (bottom) retina. Scale bar = 50 μm. (C) Length (μm) in the retina of 12 month-old zebrafish retina domains of in situ labeling. (D) Schematic summary of the location of efnb2a (pink), fgf24 (green), rdh10a (gray)-expressing Müller glia, in addition to igfbp5b/her4.1-expressing immature Müller glia and pcna-expressing ciliary margin zone progenitor cells.
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Full text @ Front. Mol. Neurosci.
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