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Figure 5
(A1) shows the upregulation of mitochondrial processes. (A2) shows the upregulation of GO terms involved in both protein metabolism and biosynthesis. (B1,B2) show the downregulation of developmental and cell cycle terms, respectively. (C) shows the upregulation of proteasomal subunit genes. (D) shows the qPCR analysis showing a significant upregulation of PSM8 and a non-significant upregulation of COX4I1. (E) shows the predicted inhibition of upstream regulator EZR. (F) shows the downregulation of genes involved in the ECM such as collagens, integrins, and fibronectins. * p < 0.05, ns = non-significant.
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