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Fig 8
ZfpA alters susceptibility to caspofungin during infection.
Survival analysis of Rac2D57N larvae (neutrophil-deficient) infected with WT CEA10, ΔzfpA, or OE::zfpA strains and bathed in 1 μg/mL caspofungin (CSP) or 0.01% DMSO. Average spore dose injected: WT CEA10 = 35, ΔzfpA = 30, OE::zfpA = 40. Results represent pooled data from 3 independent experiments. n = 50–59 larvae per condition. p values and hazard ratios calculated by Cox proportional hazard regression analysis.
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