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Figure 6
Immunohistochemical study at 3 wpf with anti-NPC1 antibody in wt (A–D) and npc1−/− individuals (E–H). The square in the top picture indicates the part of the body shown in (A,E). Wt fish (A) were anti-NPC1 positive (indicated by purple staining) in the central nervous system (A) (arrow) and (B), liver (C), intestine (C) and renal tubules (D) whereas npc1−/−larvae (E) showed no staining in central nervous system (F), liver (G), intestine (G) or renal tubules (H). Scale bars in (A,E) 200 μm. Scale bars in (B–D,F–H) 50 μm.
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Full text @ Front. Mol. Neurosci.