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FIGURE 2
The CNTFR ligands clcf1 and crlf1a, but not cntf, are differentially expressed by activated Müller glia during regeneration in the light-treated retina. The expression of clcf1 (A), crlf1a (B), cntf (C), cntfr (D), lifrb (E), and il6st (F) were examined in a single-cell RNA-Seq data set (Hoang et al., 2020). Upper violin plots show number of UMI expressed in individual resting and activated Müller glia. Percentage of Müller glia in each cluster expressing the gene of interest is shown above the plot. Lower violin plots show number of UMI expressed across time in activated Müller glia.
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