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Fig. 4 a Injection of TGF-β legend sqt mRNA and treatment of Wnt-β-catenin inhibitor ICG-001 simultaneously rescue the abnormal phenotype of the DYRK1A-overexpressed embryo. b sqt mRNA and ICG-001 also recover the ectopic expression of organizer marker genes gsc and chd in the DYRK1A-overexpressed embryo.
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