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Fig. 1
Zebrafish xenografted with patient-derived cells (PDCs) can be monitored in real-time using automatic imaging and image analysis. (A) Experiment workflow. High-throughput injection of GFP-tagged PDCs can be monitored in real-time in six 96-well plates using the IncuCyte S3. (B) Pixel-wise semantic segmentation for tumor localization and post-classification of image types. Left panel: Bright Field; Middle panel: Green Fluorescence; Right panel: post-classification. (C and D) Confusion matrices of post-segmentation image classifications for precision (C) and sensitivity (D).
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