Figure 5.

Figure 5.

Analysis of the AUC of the Hilbert transform of the LFP recordings. A, Mean baseline normalized AUC of the absolute value of the Hilbert transform of the LFP averaged into 30-s time bins. The shadows represent the SEM (n = 20–24). The left-hand side of the graph represents the baseline period, while the right-hand side represents the exposure period. The gap in time from 7 to 17 min is time allotted for compounds to take effect. B, Shows the baseline normalized AUC for each of the compounds tested. The bars show the normalized AUC averaged across all treatment groups for each compound, while the normalized AUC of individual larvae are represented as transparent grey circles. Data are shown as the mean with error bars depicting the SEM (n = 20–24). An asterisk indicates a statistically significant difference between baseline and exposure periods (p < 0.05) using Wilcoxon signed-rank test and corrected for multiple comparisons using the Benjamini and Hochberg method (Benjamini and Hochberg, 1995).