Figure 6
The circulating permeability factors in the mouse serum samples at 6 months of age. (a) The serum levels of CLCF1 were comparable among the three groups. (b) The serum levels of TNF-α were comparable among the three groups. (c) The serum levels of suPAR were significantly elevated in the Crb2fl/flpod-CreTg/+ mice compared to the Crb2fl/fl mice while there was no significant difference between serum levels of the Crb2fl/flpod-CreTg/+ mice and the Crb2+/+pod-CreTg/+ mice. Data are presented as the mean ± SD. The statistical analysis was performed by a one-way analysis of variance, followed by Scheffe's multiple comparison test; n = 5 in each group. *P < 0.05. CLCF1 cardiotrophin like cytokine factor 1, TNF-α tumor necrosis factor-α, suPAR soluble urokinase-type plasminogen activator receptor.