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Fig. 5 Overall distribution and altered expression of transcripts within the AHR Xenobiotic Response and Nrf2 Antioxidant Response pathways. Log2 fold change values and p-values (FDR) were graphed as a volcano plot, showing that the majority of significantly impacted genes were downregulated. Within the AHR and Nrf2 pathways, transcription factors ahr2 and nfe2l2b were both decreased, as were their enzymatic targets. FDR<0.05.
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