ZFIN Image: Zhang et al., 2021, Fig. 6

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Figure Caption

Fig. 6 Tumoral hypoxia imaging in mice.

Optical imaging of human breast MCF-7 tumor-xenografted mice injected with HDSF (20 μM, 50 μL). a Images (overlaps of fluorescence and bright-field images) of a mouse underwent subcutaneously (ROI A) and intratumoral (ROI B) HDSF-injection recorded at different time post injection; b images of mice bearing tumors of different size (~151 and 383 mm³) recorded at first or 20^th min post intratumoral HDSF-injection; c temporal profile of fluorescence in ROIs A and B in (a); d histogram of fluorescence in tumors in (b). Data were presented as mean ± SD. The results are representative of three independent experiments. λ_ex, 660 nm; λ_em, 710 nm. Source data are available as a Source data file.

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