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Figure 1 Morphometric and infiltrate analysis of the gut wall. Fish were fed with a soy-supplemented diet for one (T1), two (T2), three (T3), four (T4), and five (T5) weeks or normal diet (CTR). (A) The total wall thickness was found increased after two and three weeks of treatment (T2 vs. CTR, p < 0.001; T3 vs. CTR, p < 0.05). (B) The percentage of MPO-positive immune cells was found increased in the submucosal layer of SBM-treated fish starting from T2 (T2 vs. CTR, p < 0.001; T3 vs. CTR, p < 0.001; T4 vs. CTR, p < 0.001; T5 vs. CTR, p < 0.01). Significance values were set at less than p < 0.05 (*), p < 0.01 (**), and p < 0.001 (***).