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Fig. 7
A: TALEN generated 11 bp frameshift mutation allele (spo11uc73) leads to a truncated 57 aa Spo11 protein with the conserved TP6A_N and TOPRIM family domains deleted.
B: Whole testes stained for vasa (magenta), γH2AX (green), and DAPI (gray). spo11 +/-testes show a normal pattern of γH2AX staining whereas the pattern is disrupted in the spo11 -/- mutant.
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