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Fig. 3
Bevacizumab causes specific vasculature formation defects in the SIV.
(A–D) Representative fluorescent images of zebrafish embryos at 3 dpf treated with PBS (control) or bevacizumab (2 mg/mL). (A, B) In contrast, treatment with bevacizumab at the pectoral fin stage (2.5 dpf) causes specific vasculature formation defects in the SIV (B, white arrow). (C–D) Truncal vasculature of the zebrafish shows no appreciable phenotypic differences relative to control.
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