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Fig. S1
Spatiotemporal expression pattern of Dyrk1a protein in zebrafish embryos. Detection of zebrafish Dyrk1a protein using whole-mount immunohistochemistry (WIHC) at indicated stages. Arrows show the stronger expression region of Dyrk1a protein. It is shown that expression pattern of Dyrk1a protein is similar to dyrk1a transcripts detected by WISH. Embryo orientations: 2-cell, 30%-epiboly and 50%-epiboly stage, lateral views with the animal pole oriented at the top; 8-somite, Prim-5 and Prim-25 stage, lateral views with anterior oriented toward the left.
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