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Fig. 6
Figure 6 Inhibiting p53 activity abrogates apoptosis caused by PEG-b-PCL nano-micelle.
Notes: (A) TUNEL analysis of apoptosis in control, Pifithrin-α (p53 inhibitor) pretreated and p53 morpholino (p53MO) preinjected embryos with or without 240 μg/mL PEG-b-PCL exposure. (B) Mean fluorescence intensity measurement of apoptosis shown in (A). Data are expressed as mean ± SEM from three biological samples. **P<0.01.
Abbreviations: Ctrl, control; MO, morpholino; PEG-b-PCL, poly(ethylene glycol)-b-poly(ε-caprolactone); TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling; SEM, standard error of mean.
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