ZFIN ID: ZDB-IMAGE-170110-25
Figures for Xiao et al., 2016

Figure Caption/Comments:

Fig. S14

Dnmt3ab is required for myocardial proliferation. (a) Quantitative PCR showed that dnmt3ab was induced in injured hearts at 3, 7, and 14 dpa compared with sham hearts (**P <0.01; ***P <0.001; data presented are mean ± s.e.m.; paired Student’s t-test). (b) Quantitative PCR showed that nanoparticle-mediated dnmt3ab siRNA decreased the RNA level of dnmt3ab in wild-type hearts (*P <0.05; data presented are mean ± s.e.m.; unpaired Student’s t-test). (c-e) BrdU +/Mef2C+ proliferating cardiomyocytes decreased in dnmt3ab siRNA hearts (d) compared with negative control (NC) siRNA heart (c) at 14 dpa. The number (n) of hearts analyzed in each group is indicated in each bar (***P <0.001; data presented are mean ± s.e.m.; paired Student’s t-test). Scale bar, 100μm.

Figure Data:
Acknowledgments:
ZFIN wishes to thank the journal for permission to reproduce figures from this article. Please note that this material may be protected by copyright.