ZFIN Image: Viringipurampeer et al., 2014, Fig. 8

Image

Figure Caption

Fig. 8

Effect of RIP signalling inhibitors on pde6c^w59 mutant phenotype at 7 d.p.f. Retinal histology in (a) wild-type (wt), (b) untreated mutant (mt) and (c) mt retina from embryos treated with 100mM necrostatin-1s (N). White arrows in a–c indicate the photoreceptor nuclear layer of the retina. Rip1 labelling (red) in wt retina (d), in mt retina co-localizing with EGFP-expressing cones that are dying (e), and in mt retina treated with necrostatin-1s (f). (g) rip1 labelling in the retina of pde6c^w59 mutant embryos treated with 20μM necrosulfonamide (S). TUNEL labelling in non-transgenic pde6c^w59 mutant embryos (h–k) corresponding to the treatment panels (d–g) above. Scale bar in d=20μm

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

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