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Fig. S4 Zebrafish embryonic expression driven by SOX3_hs8 enhancer activating different minimal promoters: A: chicken β-globin promoter, B: zebrafish ngn 1, C: zebrafish hsp70, D: human SOX3, E: human ATP11C, F: zebrafish atp11c G: gata2 promoter, H: ATP11C-adjacent CTCF binding site and gata2 promoter. All patterns are confined to hindbrain, spinal cord, inner ear, olfactory pits and telencephalon (identical with pattern obtained with gata2 promoter used normally in our enhancer test assay). All transgenic embryos are 2 days old F1, lateral view.
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Reprinted from Developmental Biology, 327(2), Navratilova, P., Fredman, D., Hawkins, T.A., Turner, K., Lenhard, B., and Becker, T.S., Systematic human/zebrafish comparative identification of cis-regulatory activity around vertebrate developmental transcription factor genes, 526-540, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.