ZFIN Image: Aoki et al., 2002, Fig. 1

Image

Figure Caption

Fig. 1 Functional interaction between sqt, cyc, and tar. (A–D,shield stage, dorsal view) (A) Expression of gsc in control gastrulae or (B) in gastrulae overexpressing sqt RNA (0.2 pg), (C) tar RNA (100 pg), or (D) both as indicated. Note the enlargement or the duplication of the gsc domain in (D). (E–J) A similar overexpression of sqt, cyc, tar RNAs, or a combination as indicated was carried out in MZoep^m134 embryos and the expression of gsc was analysed when embryos had reached the early gastrula period (equivalent to the shield stage). (E–G, animal pole view) gsc is not expressed in control uninjected embryos or embryos overexpressing sqt, or cyc RNAs. (H–J, lateral view) tar overexpression induces a weak expression of gsc in some embryos (H) but strongly induces the ectopic expression of gsc when coexpressed with cyc or sqt (I, J).

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Reprinted from Developmental Biology, 241(2), Aoki, T.O., Mathieu, J., Saint-Etienne, L., Rebagliati, M.R., Peyriéras, N., and Rosa, F.M., Regulation of nodal signalling and mesendoderm formation by TARAM-A, a TGFbeta-related type I receptor, 273-288, Copyright (2002) with permission from Elsevier. Full text @ Dev. Biol.