ZFIN Image: Clements et al., 2005, Fig. 5

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Figure Caption

Fig. 5 LZIC morpholinos cause neural tissue degeneration. Embryos injected with 5 ng of LZIC mismatch control MO (LZICmis MO; A–C), LZIC MO1 (D–I), or LZIC MO2 (J–L) at 15 somites. Cell death is apparent in the morphants as opaque tissue (arrows, D, E, G, H, J, K) or at earlier stages of cell death fluorescently stained by acridine orange (C, F, I, L). Telencephalon (red arrows), diencephalon (yellow arrows), midbrain (orange arrowheads), eye (purple arrows), hindbrain (black arrows), and dorsal neural tube (blue arrows). (A, D, G, J) Lateral views, anterior to left. (B, C, E, F, H, I, K, L) Head views, ventral to top.

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Acknowledgments

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Reprinted from Developmental Biology, 283(2), Clements, W.K., and Kimelman, D., LZIC regulates neuronal survival during zebrafish development, 322-334, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.