Gene

etv5b

ID

ZDB-GENE-991228-4

Name

ETS variant transcription factor 5b

Symbol

etv5b Nomenclature History

Previous Names

cb805 (1)
erm1 (1)
erm
wu:fe05h04
wu:fj66a04

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Exhibits sequence-specific DNA binding activity. Involved in several processes, including limb morphogenesis; nervous system development; and pronephros development. Predicted to localize to nucleus. Is expressed in several structures, including brain; eye; mesoderm; neural plate; and pharyngeal arch. Orthologous to human ETV5 (ETS variant transcription factor 5).

Genome Resources

Note

None

Expression

All Expression Data

83 figures from 63 publications

Cross-Species Comparison

High Throughput Data

No data available

Thisse Expression Data

cb805 (34 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With etv5b Human Ortholog

No data available

Associated With etv5b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000418	Ets domain
Domain	IPR006715	PEA3-type ETS-domain transcription factor, N-terminal
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036390	Winged helix DNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Ets domain	PEA3-type ETS-domain transcription factor, N-terminal	Winged helix DNA-binding domain superfamily	Winged helix-like DNA-binding domain superfamily
UniProtKB:A0A2R8RKU6 InterPro	526
UniProtKB:A0A2R8QCK8 InterPro	507
UniProtKB:A0A2R8QC01 InterPro	526
UniProtKB:A0A2R8QLU5 InterPro	480
UniProtKB:A8E555 InterPro	524
UniProtKB:Q9PUQ2 InterPro	489
UniProtKB:F1QK52 InterPro	524
UniProtKB:Q6P952 InterPro	526