ZFIN ID: ZDB-GENE-991208-8
Gene Name: bone morphogenetic protein receptor, type IBa
Gene Symbol: bmpr1ba    Nomenclature History

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Previous Names: BMPR-IB (1), bmpr1b, BR1b, alk6, alk6tr, zALK-6, zgc:92220

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have SMAD binding activity and transforming growth factor beta receptor activity, type I. Involved in BMP signaling pathway and determination of dorsal identity. Predicted to localize to plasma membrane and receptor complex. Is expressed in several structures, including anterior neural rod; margin; nervous system; optic primordium; and ovarian follicle. Human ortholog(s) of this gene implicated in brachydactyly type A1D; brachydactyly type A2; and osteochondrodysplasia. Orthologous to human BMPR1B (bone morphogenetic protein receptor type 1B).
Genome Resources: Alliance (1),  Gene:30742 (1),  Ensembl(GRCz11):ENSDARG00000104100 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa13912 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20343 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33531 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-bmpr1ba N/A 1
    MO2-bmpr1ba N/A 1
    PHENOTYPE
    Data: Fig. 3 from Maurya et al., 2011
    Observed in:
    DISEASE ASSOCIATED WITH bmpr1ba HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    brachydactyly type A1D Alliance Brachydactyly, type A1, D 616849
    brachydactyly type A2 Alliance Brachydactyly, type A2 112600
    Acromesomelic dysplasia, Demirhan type 609441
    DISEASE ASSOCIATED WITH bmpr1ba VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process BMP signaling pathway (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 21)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA bmpr1ba-201 (1)    Ensembl 1900
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM bmpr1ba No data available
    MARKER RELATIONSHIPS
    bmpr1ba Contained in: [Fosmid] CH1073-243O2 (1)
    bmpr1ba Encodes: [EST] eu129 (1), IMAGE:7158013 (1)
    [cDNA] MGC:92220 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131457 (1) 2303 nt
    Genomic GenBank:CABZ01039094 (1) 66433 nt
    Select Tool
    Polypeptide UniProtKB:Q9W629 (1) 530 aa
    Sequence Information (all 31)
    ORTHOLOGY for bmpr1ba ( Chr: 5 )
    CITATIONS (47)