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ZIRC
ZFIN ID: ZDB-GENE-991119-5
Gene Name: iroquois homeobox 3a
Gene Symbol: irx3a    Nomenclature History

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Previous Names: iro3 (1), irx3, ziro3 (1), hm:zehn0543, id:ibd3380 (1), iro3-s1 (1), iro3-s2 (1), wu:fk88a03 (1), zehn0543, zgc:109805

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have sequence-specific DNA binding activity. Involved in endocrine pancreas development and gastrulation. Predicted to localize to the nucleus. Is expressed in several structures, including germ ring; hindbrain neural keel; nervous system; neural rod; and pancreatic system. Orthologous to human IRX3 (iroquois homeobox 3).
Genome Resources: Alliance (1),  Gene:30520 (1),  Ensembl(GRCz11):ENSDARG00000101076 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10639 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-irx3a N/A 2
    MO2-irx3a N/A 1
    DISEASE ASSOCIATED WITH irx3a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH irx3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process endocrine pancreas development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 6)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA irx3a-201 (1)    Ensembl 1848
    ncRNA irx3a-002 (1)    Ensembl 2628
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM irx3a
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(E200-irx3a:EGFP) irx3a EGFP Danio rerio 1 2
    Tg(Z176-irx3a:EGFP) irx3a EGFP Danio rerio 1 2
    MARKER RELATIONSHIPS
    irx3a Contained in: [BAC] DKEY-103G18 (1) (order this)
    irx3a Encodes: [EST] fk88a03 (2), ibd3380 (1) (order this), fa91c03 (1), zehn0543
    [cDNA] MGC:109805 (1) (order this), MGC:174145 (1) (order this), MGC:193063 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131267 (1) 2640 bp
    Genomic GenBank:CR384080 (1) 131716 bp
    Select Tool
    Polypeptide UniProtKB:A7YYJ6 (1) 454 aa
    Sequence Clusters UniGene:8282 (1)
    Sequence Information (all 35)
    ORTHOLOGY for irx3a ( Chr: 7 )
    CITATIONS (52)