Gene
opn1sw1
- ID
- ZDB-GENE-991109-25
- Name
- opsin 1 (cone pigments), short-wave-sensitive 1
- Symbol
- opn1sw1 Nomenclature History
- Previous Names
-
- SWS1 (1)
- uvops
- zfuv
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled photoreceptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to light stimulus; and detection of light stimulus. Predicted to act upstream of or within signal transduction and visual perception. Predicted to be located in membrane. Predicted to be active in photoreceptor outer segment and plasma membrane. Is expressed in several structures, including digestive system; endocrine system; heart; photoreceptor cell; and visual system. Human ortholog(s) of this gene implicated in blue color blindness. Orthologous to human OPN1SW (opsin 1, short wave sensitive).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 92 figures from 63 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73050 (2 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Yoshimatsu et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| blue color blindness | Alliance | Colorblindness, tritan | 190900 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR027430 | Visual pigments (opsins) retinal binding site |
| Domain | IPR017452 | GPCR, rhodopsin-like, 7TM |
| Family | IPR000276 | G protein-coupled receptor, rhodopsin-like |
| Family | IPR001521 | Opsin, blue sensitive |
| Family | IPR001760 | Opsin |
| Family | IPR050125 | G-protein coupled receptor opsins |
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, rhodopsin-like, 7TM | G-protein coupled receptor opsins | G protein-coupled receptor, rhodopsin-like | Opsin | Opsin, blue sensitive | Visual pigments (opsins) retinal binding site |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q9W6A9 | InterPro | 336 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
opn1sw1-201
(1)
|
Ensembl | 1,777 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab2-opn1sw1 |
|
ABclonal
|
1 | ||||
| Ab1-opn1sw1 | polyclonal | Rabbit |
|
43 |
Plasmids
No data available