Gene

opn1sw1

ID
ZDB-GENE-991109-25
Name
opsin 1 (cone pigments), short-wave-sensitive 1
Symbol
opn1sw1 Nomenclature History
Previous Names
  • SWS1 (1)
  • uvops
  • zfuv
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have G protein-coupled photoreceptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to light stimulus; and phototransduction. Predicted to localize to integral component of plasma membrane and photoreceptor outer segment. Is expressed in several structures, including digestive system; endocrine system; heart; photoreceptor cell; and visual system. Human ortholog(s) of this gene implicated in blue color blindness. Orthologous to human OPN1SW (opsin 1, short wave sensitive).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
72 figures from 51 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Yoshimatsu et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With opn1sw1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
blue color blindness Alliance Colorblindness, tritan 190900
Associated With opn1sw1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR027430 Visual pigments (opsins) retinal binding site
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR001521 Opsin, blue sensitive
Family IPR001760 Opsin
Domain Details Per Protein
Protein Length GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like Opsin Opsin, blue sensitive Visual pigments (opsins) retinal binding site
UniProtKB:Q6P981 336
UniProtKB:Q9PWN2 170
UniProtKB:Q9W6A9 336
UniProtKB:Q6NW86 336
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab2-opn1sw1
ABclonal
1
Ab1-opn1sw1 polyclonal Rabbit
  • IHC
  • WB
38
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations