Gene

ldhba

ID

ZDB-GENE-991026-6

Name

lactate dehydrogenase Ba

Symbol

ldhba Nomenclature History

Previous Names

ldhb
wu:fa16d07 (1)
wu:fa20c10 (1)
wu:fa96a08 (1)

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to have L-lactate dehydrogenase activity. Predicted to be involved in carbohydrate metabolic process; carboxylic acid metabolic process; and oxidation-reduction process. Predicted to localize to cytoplasm. Is expressed in several structures, including alar plate midbrain region; musculature system; nervous system; pronephric duct; and yolk syncytial layer. Orthologous to human LDHB (lactate dehydrogenase B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:55551 (8 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ldhba Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		[Lactate dehydrogenase-B deficiency]	614128

Associated With ldhba Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR018177	L-lactate dehydrogenase, active site
Domain	IPR001236	Lactate/malate dehydrogenase, N-terminal
Domain	IPR022383	Lactate/malate dehydrogenase, C-terminal
Family	IPR001557	L-lactate/malate dehydrogenase
Family	IPR011304	L-lactate dehydrogenase
Homologous_superfamily	IPR015955	Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Homologous_superfamily	IPR036291	NAD(P)-binding domain superfamily