Gene

sema4e

ID
ZDB-GENE-990715-7
Name
semaphorin 4e
Symbol
sema4e Nomenclature History
Previous Names
  • sema7
  • semaZ7
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have chemorepellent activity and semaphorin receptor binding activity. Predicted to be involved in several processes, including generation of neurons; negative regulation of cellular metabolic process; and ossification involved in bone maturation. Predicted to localize to extracellular space and integral component of plasma membrane. Is expressed in central nervous system; pectoral fin bud; and pharyngeal arch. Orthologous to human SEMA4D (semaphorin 4D).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Halloran et al., 1998
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sema4e Human Ortholog
No data available
Associated With sema4e Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001627 Sema domain
Domain IPR007110 Immunoglobulin-like domain
Domain IPR016201 PSI domain
Family IPR027231 Semaphorin
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Homologous_superfamily IPR036352 Sema domain superfamily
Repeat IPR002165 Plexin repeat
Domain Details Per Protein
Protein Length Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Plexin repeat PSI domain Sema domain Sema domain superfamily Semaphorin WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:Q6DC14 762
UniProtKB:F1QNC4 766
UniProtKB:F1QCZ2 762
UniProtKB:A9JT22 766
UniProtKB:A4JYS3 766
UniProtKB:Q9YHX4 766
UniProtKB:Q1MT68 766
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations