ZFIN is now using GRCz12tu for Genomic Data
Gene
ebf2
- ID
- ZDB-GENE-990715-11
- Name
- EBF transcription factor 2
- Symbol
- ebf2 Nomenclature History
- Previous Names
-
- EBF2 (1)
- coe2
- Zcoe2
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in several structures, including brain; hindbrain neural rod; midbrain neural keel; neural plate; and posterior neural keel. Orthologous to human EBF2 (EBF transcription factor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018350 | Transcription factor COE, conserved site |
| Domain | IPR002909 | IPT domain |
| Domain | IPR032200 | Transcription factor COE, DNA-binding domain |
| Domain | IPR032201 | Transcription factor COE, helix-loop-helix domain |
| Domain | IPR038006 | Transcription factor COE, IPT domain |
| Family | IPR003523 | Transcription factor COE |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR014756 | Immunoglobulin E-set |
| Homologous_superfamily | IPR038173 | Transcription factor COE, DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Immunoglobulin E-set | Immunoglobulin-like fold | IPT domain | Transcription factor COE | Transcription factor COE, conserved site | Transcription factor COE, DNA-binding domain | Transcription factor COE, DNA-binding domain superfamily | Transcription factor COE, helix-loop-helix domain | Transcription factor COE, IPT domain |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:O93375 | InterPro | 579 | |||||||||
| UniProtKB:A2BIQ0 | InterPro | 578 | |||||||||
| UniProtKB:A0A8M2BCW5 | InterPro | 580 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers