Gene

ebf2

ID

ZDB-GENE-990715-11

Name

EBF transcription factor 2

Symbol

ebf2 Nomenclature History

Previous Names

EBF2 (1)
coe2
Zcoe2

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including anterior neural plate; brain; hindbrain neural rod; midbrain neural keel; and posterior neural keel. Orthologous to human EBF2 (EBF transcription factor 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

12 figures from 7 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ebf2 Human Ortholog

No data available

Associated With ebf2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018350	Transcription factor COE, conserved site
Domain	IPR002909	IPT domain
Domain	IPR032200	Transcription factor COE, DNA-binding domain
Domain	IPR032201	Transcription factor COE, helix-loop-helix domain
Domain	IPR038006	Transcription factor COE, IPT domain
Family	IPR003523	Transcription factor COE
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR014756	Immunoglobulin E-set
Homologous_superfamily	IPR038173	Transcription factor COE, DNA-binding domain superfamily