ZFIN ID: ZDB-GENE-990714-24
Gene Name: t-complex 1
Gene Symbol: tcp1    Nomenclature History

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Previous Names: cct1 (1), CHUNP6875, fa13h08, wu:fa13h08 (1), wu:fc95g06

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have ATP binding activity and unfolded protein binding activity. Involved in Kupffer's vesicle development. Predicted to localize to the chaperonin-containing T-complex. Orthologous to human TCP1 (t-complex 1).
Genome Resources: Alliance (1),  Gene:30477 (1),  Ensembl(GRCz11):ENSDARG00000017891 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55424]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi491Tg Transgenic Insertion Unknown Unknown DNA
hi1907Tg Transgenic Insertion Intron 1 Unknown DNA
hi3564Tg Transgenic Insertion Exon 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa7506 Point Mutation Unknown Missense ENU
    sa12092 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-tcp1 N/A 1
    DISEASE ASSOCIATED WITH tcp1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tcp1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process Kupffer's vesicle development (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Conserved_site IPR002194 Chaperonin TCP-1, conserved site
    Family IPR002423 Chaperonin Cpn60/TCP-1 family
    Family IPR012715 T-complex protein 1, alpha subunit
    Family IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1)
    Homologous_superfamily IPR027409 GroEL-like apical domain superfamily
    Homologous_superfamily IPR027410 TCP-1-like chaperonin intermediate domain superfamily
    Homologous_superfamily IPR027413 GroEL-like equatorial domain superfamily
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tcp1 No data available
    MARKER RELATIONSHIPS
    tcp1 Contains: [SNP] rs3729222, rs3729223, rs3729224, rs3729225
    tcp1 Encodes: [EST] fa13h08 (1), fc95g06
    [STS] chunp6875
    [cDNA] MGC:55424 (1), MGC:77497 (1), MGC:191209 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131230 (1)
    Genomic GenBank:AF164036 275 bp
    Polypeptide UniProtKB:Q803P2 (1) 558 aa
    Sequence Information (all 48)
    ORTHOLOGY for tcp1 ( Chr: 23 )
    CITATIONS (37)