Gene

acat2

ID
ZDB-GENE-990714-22
Name
acetyl-CoA acetyltransferase 2
Symbol
acat2 Nomenclature History
Previous Names
  • etID39354.20 (1)
  • fb10a06
  • fb53f08
  • wu:fb10a06 (1)
  • wu:fb53f08 (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to enable acetyl-CoA C-acetyltransferase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be active in mitochondrion. Is expressed in central nervous system; hindbrain; liver; neurons; and yolk syncytial layer. Human ortholog(s) of this gene implicated in coronary artery disease. Orthologous to human ACAT2 (acetyl-CoA acetyltransferase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With acat2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?ACAT2 deficiency 614055
Associated With acat2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR020610 Thiolase, active site
Conserved_site IPR020613 Thiolase, conserved site
Domain IPR020616 Thiolase, N-terminal
Domain IPR020617 Thiolase, C-terminal
Family IPR002155 Thiolase
Homologous_superfamily IPR016039 Thiolase-like
Domain Details Per Protein
Protein Length Thiolase Thiolase, active site Thiolase, conserved site Thiolase, C-terminal Thiolase-like Thiolase, N-terminal
UniProtKB:Q7ZU18 395
UniProtKB:Q5SPA4 190
UniProtKB:Q5SPA3 395
UniProtKB:Q9W795 395
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations