Gene

dkk1b

ID
ZDB-GENE-990708-5
Name
dickkopf WNT signaling pathway inhibitor 1b
Symbol
dkk1b Nomenclature History
Previous Names
  • dkk1
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have co-receptor binding activity and receptor antagonist activity. Involved in several processes, including animal organ development; hepatic duct development; and sensory epithelium regeneration. Localizes to cytoplasm and extracellular region. Is expressed in several structures, including ectoderm; embryonic structure; median fin fold; pharyngeal arch; and sensory system. Human ortholog(s) of this gene implicated in anodontia. Orthologous to human DKK1 (dickkopf WNT signaling pathway inhibitor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
66 figures from 54 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dkk1b Human Ortholog
No data available
Associated With dkk1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006796 Dickkopf, N-terminal cysteine-rich
Domain IPR047304 Dickkopf-related protein 1, second cysteine-rich domain
Domain IPR048499 Dickkopf-related protein 1/2/4, C-terminal subdomain 2
Domain IPR048500 Dickkopf-related protein 1/2/4, C-terminal subdomain 1
Family IPR039863 Dickkopf related protein 1-4
Domain Details Per Protein
Protein Length Dickkopf, N-terminal cysteine-rich Dickkopf-related protein 1/2/4, C-terminal subdomain 1 Dickkopf-related protein 1/2/4, C-terminal subdomain 2 Dickkopf related protein 1-4 Dickkopf-related protein 1, second cysteine-rich domain
UniProtKB:Q9PWH3 240
UniProtKB:Q9W6D9 241
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations