Gene

opn1lw1

ID

ZDB-GENE-990604-41

Name

opsin 1 (cone pigments), long-wave-sensitive, 1

Symbol

opn1lw1 Nomenclature History

Previous Names

LWS-1 (1)
LC opsin (1)
rdops
red-sensitive opsin (1)
zfred

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to enable G protein-coupled photoreceptor activity. Acts upstream of or within photoperiodism. Predicted to be located in membrane. Predicted to be active in photoreceptor outer segment and plasma membrane. Is expressed in several structures, including digestive system; endocrine system; heart; photoreceptor cell; and visual system. Human ortholog(s) of this gene implicated in blue cone monochromacy; red color blindness; and red-green color blindness. Orthologous to several human genes including OPN1LW (opsin 1, long wave sensitive).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

72 figures from 47 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:73027 (5 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With opn1lw1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
blue cone monochromacy	Alliance	Blue cone monochromacy	303700
red color blindness	Alliance	Colorblindness, protan	303900

Associated With opn1lw1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR027430	Visual pigments (opsins) retinal binding site
Domain	IPR017452	GPCR, rhodopsin-like, 7TM
Family	IPR000276	G protein-coupled receptor, rhodopsin-like
Family	IPR000378	Opsin red/green sensitive
Family	IPR001760	Opsin
Family	IPR050125	G-protein coupled receptor opsins