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ZIRC
ZFIN ID: ZDB-GENE-990603-7
Gene Name: SMAD family member 2
Gene Symbol: smad2
Sequence Ontology ID : SO:0000704

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Previous Names: madh2, fj43c06, SMA- and MAD-related protein 2, wu:fj43c06

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(Including Attributions)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in several processes, including negative regulation of  ...
GENE EXPRESSION
All Expression Data: 12 figures from 9 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55212]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa21685 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • vu99 Point Mutation Exon 9 Premature Stop ENU
    Targeting reagents:
    DISEASE ASSOCIATED WITH smad2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH smad2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function sequence-specific DNA binding (more)
    GO Terms (all 18)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA smad2-202 (1) 1994
    smad2-204 (1) 555
    smad2-205 (1) 812
    smad2-206 (1) 1949
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES
    PLASMIDSNo data available
    MARKER RELATIONSHIPS
    smad2Contained in: [BAC] DKEY-88L16 (1) (order this), DKEY-126N10 (1) (order this)
    smad2Encodes: [EST] fj43c06
    [cDNA] MGC:55212 (1) (order this), MGC:113963 (1) (order this), MGC:192434 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001290015 (1) 3895bp
    Genomic GenBank:CR536613 (1) 174800bp
    Select Tool
    Polypeptide UniProtKB:F1Q5P5 (1) 469aa
    Sequence Clusters UniGene:79140 (1)
    Sequence Information (all 36)
    ORTHOLOGY for smad2 (Chr: 10)
    CITATIONS (76)