ZFIN ID: ZDB-GENE-990415-92
Gene Name: heat shock protein 8
Gene Symbol: hspa8
Previous Names: heat shock cognate 71-kd protein, hsc70, wu:fb01g06 (1), wu:fi48b06 (1)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 22 figures from 9 publications
Directly Submitted Expression Data: 12 figures (18 images) from Rauch et al., 2003 [fb93b09]
  1 figure (1 image) from Thisse et al., 2004 [MGC:55272]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  brain, central nervous system, eye, head (all 17) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
hi138Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la011844Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la017505Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-hspa8 (1), MO2-hspa8 (1)
    PHENOTYPE
    Data: 4 figures from 4 publications
    Observed in: brain, central nervous system, ceratohyal cartilage, cranium (all 17) expand
    DISEASE ASSOCIATED WITH hspa8 HUMAN ORTHOLOG No data available
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process fin regeneration (more)
    Molecular Function ATP binding (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR013126 (1)
  • InterPro:IPR018181 (1)
  • InterPro:IPR029047 (1)
  • InterPro:IPR029048 (1)
  • PROSITE:PS00297 (1)
  • PROSITE:PS00329 (1)
  • PROSITE:PS01036 (1)
  • Pfam:PF00012 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA hspa8-001 (1) 2453
    hspa8-002 (1) 675
    hspa8-003 (1) 678
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hspa8
    Tg(hspa8:mAGFP-Hsa.GMNN.110), Tg(hspa8:MITO-YC2), Tg(hspa8:mKOFP2-Hsa.CDT1.120), Tg(hspa8:YC2)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    hspa8Contained in: [BAC] RP71-56I13 (1) (order this)
    hspa8Encodes: [EST] fb93b09 (1) (order this), fi48b06 (1)
    [cDNA] MGC:55272 (1) (order this), MGC:76861 (1) (order this), MGC:77588 (1) (order this), MGC:173731 (1) (order this), MGC:192805 (1) (order this)
    hspa8Has Artifact: [EST] fb01g06
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001110403 (1) 2403bp
    Genomic GenBank:BX120005 (1) 129782bp
    Select Tool
    Polypeptide UniProtKB:P79984 (1) 649aa
    Sequence Clusters UniGene:75087 (1)
    Sequence Information (all 42)
    OTHER hspa8 GENE PAGES 
  • Gene:573376 (1)
  • VEGA:OTTDARG00000008420 (1)
  • Ensembl(GRCz10):ENSDARG00000068992 (1)
  • ORTHOLOGY for hspa8 (Chr: 10) 
    Species Symbol Chromosome Accession # Evidence
    Human HSPA8 11
  • Gene:3312
  • OMIM:600816
  • HGNC:5241
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (60)