ZFIN ID: ZDB-GENE-990415-92
Gene Name: heat shock protein 8
Gene Symbol: hspa8
Previous Names: heat shock cognate 71-kd protein, hsc70, wu:fb01g06 (1), wu:fi48b06 (1)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 22 figures from 9 publications
Directly Submitted Expression Data: 12 figures (18 images) from Rauch et al., 2003 [fb93b09]
  1 figure (1 image) from Thisse et al., 2004 [MGC:55272]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  brain, central nervous system, eye, head (all 17) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi138Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la011844Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la017505Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41685 Point Mutation Unknown Unknown ENU
    Targeting reagents: MO1-hspa8 (1), MO2-hspa8 (1)
    PHENOTYPE
    Data: 4 figures from 4 publications
    Observed in: brain, central nervous system, ceratohyal cartilage, cranium (all 17) expand
    DISEASE ASSOCIATED WITH hspa8 HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process fin regeneration (more)
    Molecular Function ATP binding (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR013126 (1)
  • InterPro:IPR018181 (1)
  • InterPro:IPR029047 (1)
  • InterPro:IPR029048 (1)
  • PROSITE:PS00297 (1)
  • PROSITE:PS00329 (1)
  • PROSITE:PS01036 (1)
  • Pfam:PF00012 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA hspa8-001 (1) 2453
    hspa8-002 (1) 675
    hspa8-003 (1) 678
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM hspa8
    Tg(hspa8:mAGFP-Hsa.GMNN.110), Tg(hspa8:MITO-YC2), Tg(hspa8:mKOFP2-Hsa.CDT1.120), Tg(hspa8:YC2)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    hspa8Contained in: [BAC] RP71-56I13 (1) (order this)
    hspa8Encodes: [EST] fb93b09 (1) (order this), fi48b06 (1)
    [cDNA] MGC:55272 (1) (order this), MGC:76861 (1) (order this), MGC:77588 (1) (order this), MGC:173731 (1) (order this), MGC:192805 (1) (order this)
    hspa8Has Artifact: [EST] fb01g06
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001110403 (1) 2403bp
    Genomic GenBank:BX120005 (1) 129782bp
    Select Tool
    Polypeptide UniProtKB:P79984 (1) 649aa
    Sequence Clusters UniGene:75087 (1)
    Sequence Information (all 43)
    OTHER hspa8 GENE PAGES
  • Gene:573376 (1)
  • VEGA:OTTDARG00000008420 (1)
  • Ensembl(GRCz10):ENSDARG00000068992 (1)
  • ORTHOLOGY for hspa8 (Chr: 10)
    Species Symbol Chromosome Accession # Evidence
    Human HSPA8 11
  • Gene:3312
  • OMIM:600816
  • HGNC:5241
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (62)