ZFIN ID: ZDB-GENE-990415-92
Gene Name: heat shock protein 8
Gene Symbol: hspa8

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Previous Names: heat shock cognate 71-kd protein, hsc70, wu:fb01g06 (1), wu:fi48b06 (1)

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(Including Attributions)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 22 figures from 9 publications
Directly Submitted Expression Data: 12 figures (18 images) from Rauch et al., 2003 [fb93b09]
  1 figure (1 image) from Thisse et al., 2004 [MGC:55272]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  brain, central nervous system, eye, head (all 17) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi138Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la011844Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la017505Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41685 Point Mutation Unknown Premature Stop ENU
    Targeting reagents: MO1-hspa8 (1), MO2-hspa8 (1)
    PHENOTYPE
    Data: 4 figures from 4 publications
    Observed in: brain, central nervous system, ceratohyal cartilage, cranium (all 17) expand
    DISEASE ASSOCIATED WITH hspa8 HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of receptor-mediated endocytosis (more)
    Molecular Function ATP binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR013126 (1)
  • InterPro:IPR018181 (1)
  • InterPro:IPR029047 (1)
  • InterPro:IPR029048 (1)
  • PROSITE:PS00297 (1)
  • PROSITE:PS00329 (1)
  • PROSITE:PS01036 (1)
  • Pfam:PF00012 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA hspa8-001 (1) 2453
    hspa8-002 (1) 675
    hspa8-003 (1) 678
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM hspa8
    Tg(hspa8:mAGFP-Hsa.GMNN.110), Tg(hspa8:MITO-YC2), Tg(hspa8:mKOFP2-Hsa.CDT1.120), Tg(hspa8:YC2)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    hspa8Contained in: [BAC] RP71-56I13 (1) (order this)
    hspa8Encodes: [EST] fb93b09 (1) (order this), fi48b06 (1)
    [cDNA] MGC:55272 (1) (order this), MGC:76861 (1) (order this), MGC:77588 (1) (order this), MGC:173731 (1) (order this), MGC:192805 (1) (order this)
    hspa8Has Artifact: [EST] fb01g06
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001110403 (1) 2403bp
    Genomic GenBank:BX120005 (1) 129782bp
    Select Tool
    Polypeptide UniProtKB:P79984 (1) 649aa
    Sequence Clusters UniGene:75087 (1)
    Sequence Information (all 43)
    OTHER hspa8 GENE PAGES
  • Gene:573376 (1)
  • VEGA:OTTDARG00000008420 (1)
  • Ensembl(GRCz10):ENSDARG00000068992 (1)
  • ORTHOLOGY for hspa8 (Chr: 10)
    Species Symbol Chromosome Accession # Evidence
    Human HSPA8 11
  • Gene:3312
  • OMIM:600816
  • HGNC:5241
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (63)