Gene
gata3
- ID
- ZDB-GENE-990415-82
- Name
- GATA binding protein 3
- Symbol
- gata3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including embryonic organ morphogenesis; generation of neurons; and tissue regeneration. Predicted to localize to nucleus. Is expressed in several structures, including digestive system; ectoderm; nervous system; neural tube; and pleuroperitoneal region. Used to study hypoparathyroidism-retardation-dysmorphism syndrome. Human ortholog(s) of this gene implicated in hypoparathyroidism; hypoparathyroidism-deafness-renal disease syndrome; nephrosis; and sensorineural hearing loss. Orthologous to human GATA3 (GATA binding protein 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 82 figures from 51 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb550 (29 images)
Wild Type Expression Summary
- All Phenotype Data
- 16 figures from 6 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypoparathyroidism-deafness-renal disease syndrome | Alliance | Hypoparathyroidism, sensorineural deafness, and renal dysplasia | 146255 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Transcription factor GATA | Transcription factor, GATA-2/3 | Transcription factor GATA-3 | Zinc finger, GATA-type | Zinc finger, NHR/GATA-type |
|---|---|---|---|---|---|---|
|
UniProtKB:Q91428
|
438 | |||||
|
UniProtKB:B3DGG5
|
438 |
Interactions and Pathways
No data available
Plasmids
No data available