Gene

nr5a2

ID
ZDB-GENE-990415-79
Name
nuclear receptor subfamily 5, group A, member 2
Symbol
nr5a2 Nomenclature History
Previous Names
  • ff1a (1)
  • ftz
  • ftzf1
  • LRH1 (1)
  • sf1
  • zFF1 (1)
  • zFF1A (1)
  • zFF1B (1)
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Enables DNA binding activity and DNA-binding transcription factor activity. Acts upstream of or within several processes, including cartilage development; digestive system development; and hepatoblast differentiation. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including digestive system; endocrine system; head; nervous system; and slow muscle cell. Orthologous to human NR5A2 (nuclear receptor subfamily 5 group A member 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
30 figures from 17 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
10 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nr5a2 Human Ortholog
No data available
Associated With nr5a2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000536 Nuclear hormone receptor, ligand-binding domain
Domain IPR001628 Zinc finger, nuclear hormone receptor-type
Family IPR001723 Nuclear hormone receptor
Family IPR016355 Nuclear hormone receptor family 5
Homologous_superfamily IPR013088 Zinc finger, NHR/GATA-type
Homologous_superfamily IPR035500 Nuclear hormone receptor-like domain superfamily
Domain Details Per Protein
Protein Length Nuclear hormone receptor Nuclear hormone receptor family 5 Nuclear hormone receptor, ligand-binding domain Nuclear hormone receptor-like domain superfamily Zinc finger, NHR/GATA-type Zinc finger, nuclear hormone receptor-type
UniProtKB:Q9DFB4 27
UniProtKB:Q90YL6 517
UniProtKB:Q9DFB5 17
UniProtKB:O42557 36
UniProtKB:O42186 516
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations