ZFIN ID: ZDB-GENE-990415-79
Gene Name: nuclear receptor subfamily 5, group A, member 2
Gene Symbol: nr5a2
Sequence Ontology ID : SO:0000704

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Previous Names: ff1a (1), ftz, ftzf1, LRH1 (1), sf1, zFF1 (1), zFF1A (1), zFF1B (1)

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(Including Attributions)
Location: Chr: 22 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits DNA binding activity and DNA-binding activity transcription factor activity; involved in several processes, including animal organ development, digestive system development, and regulation  ...
GENE EXPRESSION
All Expression Data: 30 figures from 17 publications
Directly Submitted Expression Data: 6 figures (29 images) from Thisse et al., 2008 [ay034061]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb193 Indel Exon 2 Unknown TALEN
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
  • ihb195 Small Deletion Exon 2 Unknown TALEN
    la022261Tg Transgenic Insertion Unknown Unknown DNA
    oz3 Insertion Exon 3 Frameshift, Premature Stop TALEN
    sa37512 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37513 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43841 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44987 Point Mutation Unknown Unknown ENU
    Targeting reagents:
    PHENOTYPE
    Data: 10 figures from 3 publications
    Observed in:
    DISEASE ASSOCIATED WITH nr5a2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nr5a2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 20)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000536 (1)
  • InterPro:IPR001628 (1)
  • InterPro:IPR001723 (1)
  • InterPro:IPR013088 (1)
  • InterPro:IPR016355 (1)
  • InterPro:IPR035500 (1)
  • PROSITE:PS00031 (1)
  • PROSITE:PS51030 (1)
  • PROSITE:PS51843 (1)
  • Pfam:PF00104 (1)
  • Pfam:PF00105 (1)
  •  Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM nr5a2 No data available
    MARKER RELATIONSHIPS
    nr5a2Contained in: [BAC] CH211-212L17 (1) (order this)
    nr5a2Encodes: [EST] ay034061 (1) (order this)
    [cDNA] MGC:195042 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131463 (1) 3126bp
    Genomic GenBank:AL954148 (1) 201639bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q90YL6 (1) 517aa
    Sequence Clusters UniGene:6870 (1)
    Sequence Information (all 29)
    OTHER nr5a2 GENE PAGES
  • Alliance (1)
  • Gene:30749 (1)
  • Ensembl(GRCz11):ENSDARG00000100940 (1)
  • ORTHOLOGY for nr5a2 (Chr: 22)
    CITATIONS (51)