ZFIN ID: ZDB-GENE-990415-63
Gene Name: eph receptor A2 a
Gene Symbol: epha2a    Nomenclature History

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Previous Names: epha2, id:ibd5152 (1), rtk6

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have transmembrane-ephrin receptor activity. Predicted to be involved in axon guidance; positive regulation of kinase activity; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to localize to integral component of plasma membrane; neuron projection; and receptor complex. Is expressed in tail bud. Human ortholog(s) of this gene implicated in cataract 6 multiple types. Orthologous to human EPHA2 (EPH receptor A2).
Genome Resources: Alliance (1),  Gene:30689 (1),  Ensembl(GRCz11):ENSDARG00000017354 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 5 figures (9 images) from Kudoh et al., 2001 [ibd5152]
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH epha2a HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
cataract 6 multiple types Alliance Cataract 6, multiple types 116600
DISEASE ASSOCIATED WITH epha2a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process phosphorylation (more)
Cellular Component integral component of membrane (more)
Molecular Function ATP binding (more)
GO Terms (all 20)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA epha2a-201 (1)    Ensembl 3607
ncRNA epha2a-002 (1)    Ensembl 638
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM epha2a No data available
MARKER RELATIONSHIPS
epha2a Contained in: [BAC] CH73-312E21 (1), DKEY-148L2 (1) (order this)
epha2a Encodes: [EST] ibd5152 (1)
[cDNA] MGC:76910 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_131415 (1) 3620 nt
Genomic GenBank:BX663614 (1) 191715 nt
Select Tool
Polypeptide UniProtKB:F1QSD6 (1) 984 aa
Sequence Information (all 15)
ORTHOLOGY for epha2a ( Chr: 6 )
CITATIONS (35)