Gene

c3a.1

ID
ZDB-GENE-990415-35
Name
complement C3a, tandem duplicate 1
Symbol
c3a.1 Nomenclature History
Previous Names
  • C3-1 (1)
  • c3.1 (1)
  • c3a
  • cb26 (1)
  • sb:cb26 (1)
  • si:dkey-76b14.4
  • wu:fi34b03
  • wu:fj86e11
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Is predicted to enable endopeptidase inhibitor activity. Acts upstream of or within chordate embryonic development. Predicted to be located in extracellular space. Is expressed in several structures, including gill; heart; liver; pleuroperitoneal region; and yolk syncytial layer. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; complement deficiency (multiple); macular degeneration (multiple); paroxysmal nocturnal hemoglobinuria; and sickle cell anemia. Orthologous to human C3 (complement C3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
25 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With c3a.1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
age related macular degeneration 9 Alliance {Macular degeneration, age-related, 9} 611378
complement component 3 deficiency Alliance C3 deficiency 613779
{Hemolytic uremic syndrome, atypical, susceptibility to, 5} 612925
Associated With c3a.1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Protein Length
UniProtKB:A0A8M1P7C1 1643
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations