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ZIRC
ZFIN ID: ZDB-GENE-990415-198
Gene Name: teratocarcinoma-derived growth factor 1
Gene Symbol: tdgf1
Sequence Ontology ID : SO:0000704

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Previous Names: cb85 (1), cripto, oep, one eyed pinhead, one-eyed pinhead, wu:fe01d04, zgc:109829

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(Including Attributions)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have activin receptor binding activity and nodal binding activity. Involved in several processes, including animal organ development; embryonic morphogenesis; and regionalization.  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ko202 Point Mutation Exon 3 Premature Stop CRISPR
la017432Tg Transgenic Insertion Unknown Unknown DNA
m134 Point Mutation Unknown Premature Stop ENU
tdgf1_unspecified Unspecified Unknown Unknown
tz257 Point Mutation Start Codon Start Loss ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • z1 Deficiency Unknown Unknown G_RAYS
    Targeting reagents:
    PHENOTYPE
    Data: 62 figures from 40 publications
    Observed in:
    DISEASE ASSOCIATED WITH tdgf1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Forebrain defects
    DISEASE ASSOCIATED WITH tdgf1 VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    neural tube defect tdgf1m134/m134 standard conditions Ma et al., 2015
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process floor plate formation (more)
    Cellular Component external side of plasma membrane (more)
    Molecular Function activin receptor binding (more)
    GO Terms (all 46)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR013032 (1)
  • InterPro:IPR019011 (1)
  • PROSITE:PS00022 (1)
  • Pfam:PF09443 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tdgf1 No data available
    MARKER RELATIONSHIPS
    tdgf1Encodes: [EST] cb85 (1) (order this), fe01d04
    [cDNA] MGC:109829 (1) (order this), MGC:173598 (1) (order this), MGC:174150 (1) (order this), MGC:192394 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131092 (1) 1535bp
    Genomic GenBank:CABZ01070743 (1) 6287bp
    Polypeptide UniProtKB:F1Q691 (1) 190aa
    Sequence Clusters UniGene:52009 (1)
    Sequence Information (all 36)
    OTHER tdgf1 GENE PAGES
  • Alliance (1)
  • Gene:30304 (1)
  • Ensembl(GRCz11):ENSDARG00000035095 (1)
  • ORTHOLOGY for tdgf1 (Chr: 10)
    CITATIONS (278)