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Gene

ntn1b

ID
ZDB-GENE-990415-168
Name
netrin 1b
Symbol
ntn1b Nomenclature History
Previous Names
  • net1 (1)
  • ntn1
  • etID309922.3 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Acts upstream of or within neuron projection development and regulation of axon extension. Predicted to be located in extracellular region. Predicted to be active in basement membrane. Is expressed in several structures, including central nervous system; forebrain neural rod; head; hypochord; and neural plate. Human ortholog(s) of this gene implicated in congenital mirror movement disorder. Orthologous to human NTN1 (netrin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
25 figures from 18 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Zhang et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ntn1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Mirror movements 4 618264
Associated With ntn1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001134 Netrin domain
Domain IPR002049 Laminin EGF domain
Domain IPR008211 Laminin, N-terminal
Domain IPR018933 Netrin module, non-TIMP type
Homologous_superfamily IPR008979 Galactose-binding-like domain superfamily
Homologous_superfamily IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold
Homologous_superfamily IPR038684 Laminin, N-terminal domain superfamily
Domain Details Per Protein
Protein Length Galactose-binding-like domain superfamily Laminin EGF domain Laminin, N-terminal Laminin, N-terminal domain superfamily Netrin domain Netrin module, non-TIMP type Tissue inhibitor of metalloproteinases-like, OB-fold
UniProtKB:F1QUK5 602
UniProtKB:B0CM04 601
UniProtKB:A0A0B5JK74 458
UniProtKB:B3DJ84 602
UniProtKB:O42203 602
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations