ZFIN ID: ZDB-GENE-990415-166
Gene Name: NRAS proto-oncogene, GTPase
Gene Symbol: nras
Sequence Ontology ID : SO:0000704

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Previous Names: etID18709.8 (1), fj99a10, wu:fj99a10 (1), zgc:100761, zras-b1 (1)

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(Including Attributions)
Location: Chr: 8 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have GTP binding activity and GTPase activity; predicted to be involved in signal transduction; predicted to localize to the Golgi membrane and plasma membrane; orthologous to human NRAS  ...
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTSNo data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH nras HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
autoimmune lymphoproliferative syndrome type 4 ?RAS-associated autoimmune lymphoproliferative syndrome type IV, somatic 614470
colorectal cancer Colorectal cancer, somatic 114500
epidermal nevus Epidermal nevus, somatic 162900
follicular thyroid carcinoma Thyroid carcinoma, follicular, somatic 188470
Noonan syndrome 6 Noonan syndrome 6 613224
Schimmelpenning-Feuerstein-Mims syndrome, somatic mosaic 163200
Neurocutaneous melanosis, somatic 249400
Melanocytic nevus syndrome, congenital, somatic 137550
DISEASE ASSOCIATED WITH nras VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process signal transduction (more)
Cellular Component Golgi apparatus (more)
Molecular Function GTPase activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001806 (1)
  • InterPro:IPR005225 (1)
  • InterPro:IPR020849 (1)
  • InterPro:IPR027417 (1)
  • PROSITE:PS51421 (1)
  • Pfam:PF00071 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nras-201 (1) 2636
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM nras No data available
    MARKER RELATIONSHIPS
    nrasContained in: [BAC] CH73-77L8 (1) (order this), DKEYP-31A2 (1)
    nrasEncodes: [EST] fj99a10 (1)
    [cDNA] MGC:100761 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131145 (1) 2638bp
    Genomic GenBank:CT027601 (1) 81048bp
    Select Tool
    Polypeptide UniProtKB:P79737 (1) 188aa
    Sequence Clusters UniGene:233 (1)
    Sequence Information (all 16)
    OTHER nras GENE PAGES
  • Alliance (1)
  • Gene:30380 (1)
  • VEGA:OTTDARG00000028753 (1)
  • Ensembl(GRCz11):ENSDARG00000038225 (2)
  • ORTHOLOGY for nras (Chr: 8)
    CITATIONS (35)