ZFIN ID: ZDB-GENE-990415-156
Gene Name: melatonin receptor 1Bb
Gene Symbol: mtnr1bb    Nomenclature History

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Previous Names: mel1br, mtnr1br, zMel1b-1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to localize to plasma membrane. Is expressed in caudal tuberal nucleus; dorsal caudal thalamic nucleus; periventricular grey zone; periventricular nucleus; and periventricular nucleus of caudal tuberculum. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human MTNR1B (melatonin receptor 1B).
Genome Resources: Alliance (1),  Gene:30668 (1),  Ensembl(GRCz11):ENSDARG00000086493 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH mtnr1bb HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
type 2 diabetes mellitus Alliance {Diabetes mellitus, type 2, susceptibility to} 125853
DISEASE ASSOCIATED WITH mtnr1bb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process G protein-coupled receptor signaling pathway (more)
Cellular Component integral component of membrane (more)
Molecular Function G protein-coupled receptor activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA mtnr1bb-201 (1)    Ensembl 1420
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM mtnr1bb No data available
MARKER RELATIONSHIPS
mtnr1bb Contained in: [BAC] CH211-214K5 (1), CH211-224H1 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_131394 (1) 1420 nt
Genomic GenBank:BX897671 (1) 201108 nt Blast at MegaBLAST
Polypeptide UniProtKB:P51049 (1) 347 aa
Sequence Information (all 10)
ORTHOLOGY for mtnr1bb ( Chr: 10 )
CITATIONS (25)