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ZIRC
ZFIN ID: ZDB-GENE-990415-153
Gene Name: MDM2 proto-oncogene
Gene Symbol: mdm2
Sequence Ontology ID : SO:0000704

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Previous Names: etID309863.4 (1), sb:eu923, zgc:109834

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(Including Attributions)
Location: Chr: 4 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have metal ion binding activity and transferase activity. Involved in several processes, including negative regulation of apoptotic process; negative regulation of cell cycle arrest; and  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa14240 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16808 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20278 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa26298 Point Mutation Unknown Splice Site ENU
    sq25 Small Deletion Exon 7 Premature Stop ZINC_FINGER_NUCLEASE
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sq26 Insertion Exon 7 Premature Stop ZINC_FINGER_NUCLEASE
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sq27 Insertion Exon 7 Premature Stop ZINC_FINGER_NUCLEASE
    sq28 Small Deletion Exon 7 Inframe Deletion ZINC_FINGER_NUCLEASE
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH mdm2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    {Accelerated tumor formation, susceptibility to} 614401
    DISEASE ASSOCIATED WITH mdm2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (more)
    Cellular Component cytoplasm (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 15)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA mdm2-001 (1) 1885
    mdm2-002 (1) 642
    mdm2-003 (1) 294
    mdm2-004 (1) 607
    mdm2-006 (1) 400
    mRNA mdm2-201 (1) 1965
    mdm2-206 (1) 584
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM mdm2
    MARKER RELATIONSHIPS
    mdm2Contained in: [BAC] CH211-149P5 (1) (order this), DKEYP-86A5 (1)
    mdm2Encodes: [EST] eu923 (1), fc16b11
    [cDNA] MGC:109834 (1) (order this), MGC:113866 (1) (order this), MGC:192439 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131364 (1) 1788bp
    Genomic GenBank:AL929141 (1) 182116bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4ISQ1 (1) 486aa
    Sequence Clusters UniGene:75764 (1)
    Sequence Information (all 40)
    ORTHOLOGY for mdm2 (Chr: 4)
    CITATIONS (135)