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ZIRC
ZFIN ID: ZDB-GENE-990415-136
Gene Name: LIM domain binding 2a
Gene Symbol: ldb2a
Sequence Ontology ID : SO:0001217

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Previous Name: ldb2 (1)

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(Including Attributions)
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits chromatin binding activity. Involved in negative regulation of BMP signaling pathway; negative regulation of nodal signaling pathway; and sprouting angiogenesis. Predicted to localize to the  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027568Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35760 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • um91 Insertion Unknown Frameshift, Premature Stop ZINC_FINGER_NUCLEASE
    um93 Small Deletion Exon 1 Splice Site ZINC_FINGER_NUCLEASE
    Targeting reagents:
    PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH ldb2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ldb2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of BMP signaling pathway (more)
    Cellular Component nucleus (more)
    Molecular Function chromatin binding (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR029005 (1)
  • InterPro:IPR030174 (1)
  • InterPro:IPR041363 (1)
  • Pfam:PF01803 (1)
  • Pfam:PF17916 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ldb2a-201 (1) 7351
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ldb2a No data available
    MARKER RELATIONSHIPS
    ldb2a Contained in: [BAC] CH73-17B5 (1) (order this), CH211-46C16 (1) (order this), CH211-186M20 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131314 (1) 1596 bp
    Genomic GenBank:CU855906 (1) 104473 bp
    Select Tool
    Polypeptide UniProtKB:F8W338 (1) 439 aa
    Sequence Clusters UniGene:599 (1)
    Sequence Information (all 19)
    ORTHOLOGY for ldb2a ( Chr: 14 )
    CITATIONS (27)