ZFIN ID: ZDB-GENE-990415-120
Gene Name: homeobox D3a
Gene Symbol: hoxd3a    Nomenclature History

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Previous Names: hoxd3, im:7144208 (1), Z-56

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification; embryonic skeletal system morphogenesis; and positive regulation of transcription by RNA polymerase II. Predicted to localize to the nucleus. Is expressed in several structures, including hindbrain; hindbrain neural keel; neural tube; pectoral fin bud; and spinal cord. Orthologous to human HOXD3 (homeobox D3).
Genome Resources: Alliance (1),  Gene:30349 (1),  Ensembl(GRCz11):ENSDARG00000059280 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026776Tg Transgenic Insertion Unknown Unknown DNA
la026777Tg Transgenic Insertion Unknown Unknown DNA
la026778Tg Transgenic Insertion Unknown Unknown DNA
la029548Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la029549Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21417 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38720 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-hoxd3a N/A 1
    MO2-hoxd3a N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH hoxd3a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hoxd3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process multicellular organism development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Conserved_site IPR001827 Homeobox protein, antennapedia type, conserved site
    Conserved_site IPR017970 Homeobox, conserved site
    Domain IPR001356 Homeobox domain
    Domain IPR020479 Homeobox domain, metazoa
    Domain IPR025281 Domain of unknown function DUF4074
    Homologous_superfamily IPR009057 Homeobox-like domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hoxd3a-203 (1)    Ensembl 1970
    ncRNA hoxd3a-002 (1) 480
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM hoxd3a No data available
    MARKER RELATIONSHIPS
    hoxd3a Contained in: [BAC] RP71-78H1 (1)
    hoxd3a Encodes: [EST] IMAGE:7144208 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131125 (1) 1825 nt
    Genomic GenBank:BX322661 (1) 146527 nt
    Select Tool
    Polypeptide UniProtKB:O42370 (1) 396 aa
    Sequence Information (all 15)
    ORTHOLOGY for hoxd3a ( Chr: 9 )
    CITATIONS (51)