Gene

hoxd13a

ID
ZDB-GENE-990415-119
Name
homeobox D13a
Symbol
hoxd13a Nomenclature History
Previous Names
  • hoxd-13
  • hoxd13
  • zgc:110511
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in multicellular organism development and regulation of transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in several structures, including cloaca; mesenchyme; pectoral fin bud; periderm; and tail bud. Human ortholog(s) of this gene implicated in brachydactyly-syndactyly syndrome; clubfoot; cryptorchidism; and dysostosis (multiple). Orthologous to human HOXD13 (homeobox D13).
Genome Resources
Note
None
Expression
All Expression Data
20 figures from 12 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hoxd13a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
brachydactyly type D Alliance Brachydactyly, type D 113200
brachydactyly type E1 Alliance Brachydactyly, type E 113300
brachydactyly-syndactyly syndrome Alliance ?Brachydactyly-syndactyly syndrome 610713
syndactyly type 5 Alliance Syndactyly, type V 186300
synpolydactyly Alliance Synpolydactyly 1 186000
Associated With hoxd13a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily
UniProtKB:B0S5Z0 256
UniProtKB:Q90472 256
UniProtKB:A8E5N0 256
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations