Gene

hoxb3a

ID

ZDB-GENE-990415-104

Name

homeobox B3a

Symbol

hoxb3a Nomenclature History

Previous Names

hoxb3
id:ibd3053 (1)
wu:fc33f11
Z-92
zgc:111819

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification; embryonic skeletal system morphogenesis; and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including ectoderm; hindbrain neural keel; nervous system; neural crest; and pharyngeal arch. Orthologous to human HOXB3 (homeobox B3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

38 figures from 28 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hoxb3a Human Ortholog

No data available

Associated With hoxb3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR001827	Homeobox protein, antennapedia type, conserved site
Conserved_site	IPR017970	Homeobox, conserved site
Domain	IPR001356	Homeobox domain
Domain	IPR020479	Homeobox domain, metazoa
Domain	IPR025281	Domain of unknown function DUF4074
Homologous_superfamily	IPR009057	Homeobox-like domain superfamily

Domain Details Per Protein

Protein	Length	Domain of unknown function DUF4074	Homeobox, conserved site	Homeobox domain	Homeobox domain, metazoa	Homeobox-like domain superfamily	Homeobox protein, antennapedia type, conserved site
UniProtKB:E9QCP3 InterPro	92
UniProtKB:O42368 InterPro	417
UniProtKB:E9QE11 InterPro	113

Transcripts

Genome Browsers

Type	Name	Length (nt)	Analysis
mRNA	hoxb3a-201 (1) Ensembl	3411 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	hoxb3a-202 (1) Ensembl	593 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	hoxb3a-203 (1) Ensembl	539 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	hoxb3a-204 (1) Ensembl	1764 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	ottdart00000001814 (1)	2771 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

Addgene:pBS ZfHoxb3a

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations