ZFIN ID: ZDB-GENE-990415-104
Gene Name: homeobox B3a
Gene Symbol: hoxb3a    Nomenclature History

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Previous Names: hoxb3, id:ibd3053 (1), wu:fc33f11, Z-92, zgc:111819

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification; embryonic skeletal system morphogenesis; and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including ectoderm; hindbrain neural keel; nervous system; neural crest; and pharyngeal arch. Orthologous to human HOXB3 (homeobox B3).
Genome Resources: Alliance (1),  Gene:30339 (1),  Ensembl(GRCz11):ENSDARG00000029263 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la011402Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la024019Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la024020Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la024021Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la024023Tg Transgenic Insertion Unknown Unknown DNA
    la024024Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17382 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-hoxb3a N/A 1
    MO2-hoxb3a N/A 1
    MO3-hoxb3a N/A 1
    MO4-hoxb3a N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH hoxb3a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hoxb3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process multicellular organism development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hoxb3a-201 (1)    Ensembl 3411
    hoxb3a-202 (1)    Ensembl 593
    hoxb3a-203 (1)    Ensembl 539
    hoxb3a-204 (1)    Ensembl 1764
    ottdart00000001814 (1) 2771
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM hoxb3a
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(hoxb3a-SCP1:Ocu.Hbb2-Cre-2A-Cerulean) hoxb3a 2ACeruleanCre Danio rerioOryctolagus cuniclus 1 1
    Tg(hoxb3a:GFP) hoxb3a GFP Danio rerio 4 2
    MARKER RELATIONSHIPS
    hoxb3a Contained in: [BAC] CH211-72A16 (1), DKEY-178D9 (1) (order this)
    [PAC] BUSM1-254O17 (2)
    hoxb3a Encodes: [EST] fc33f11 (1), ibd3053 (1)
    [cDNA] MGC:111819 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131117 (1) 2107 nt
    Genomic GenBank:BX927395 (1) 152987 nt
    Select Tool
    Polypeptide UniProtKB:O42368 (1) 417 aa
    Sequence Information (all 45)
    ORTHOLOGY for hoxb3a ( Chr: 3 )
    CITATIONS (84)